Genetic Signatures for Progression and Response of Hepatitis C: Apoptosis and Hepatitis C: Genetic and Hormonal Predictors - Image 1

£67.00

LAP Lambert Academic Publishing Genetic Signatures for Progression and Response of Hepatitis C: Apoptosis and Hepatitis C: Genetic and Hormonal Predictors

Name: Genetic Signatures for Progression and Response of Hepatitis C: Apoptosis and Hepatitis C: Genetic and Hormonal Predictors
Brand: LAP Lambert Academic Publishing
Price: 67.0 GBP
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Medical & Healthcare Practitioners

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Description

The hepatitis C virus (HCV), the silent killer, is endemic worldwide. Therefor, finding novel signatures for HCV progression and response to anti-viral therapies is very important in terms of diagnosis and prognosis of the disease. P53 induces the expression of Fas for triggering apoptosis; an important mechanism for limiting viral replication. This study aims at investigating the impact of P53 rs 1042522 and Fas rs 1800682 genetic polymorphisms at 72 Arg/Pro and -670 A/G respectively on HCV susceptibility and treatment response. Quantitation of HCV-RNA by qRT-PCR and histological scores were performed for every patient, as well as genotyping of HCV-RNA, P53 at 72 Arg/Pro, and Fas at -670 A/G polymorphisms were done for all subjects. In addition, hormonal profiling for all patients and controls were investigated and correlated with the genetic signatures, providing a strong multi-signatures for HCV progression and response.

Product Specifications

Brand: LAP Lambert Academic Publishing
Format: paperback
ASIN: 3659770566
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners
Domain: Amazon UK
Release Date: 21 August 2015
Listed Since: 13 September 2015

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LAP Lambert Academic Publishing Genetic Signatures for Progression and Response of Hepatitis C: Apoptosis and Hepatitis C: Genetic and Hormonal Predictors

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