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LAP Lambert Academic Publishing Solubility Enhancement of Certain Drugs by Solid Dispersion Technique

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£53.00 £50.35 £51.41 £52.47 £53.53 £54.59 £55.65 25 July 2026 09 August 2026 24 August 2026 08 September 2026 23 September 2026
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Price distribution over 61 days • 1 price levels

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61 days 0 15 31 46 61 £53 Days at Price

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Most common price: £53 (61 days, 100.0%)

Price range: £53 - £53

Price levels: 1 different prices over 61 days

Description

Recent advances in novel drug delivery systems (NDDS) aim to enhance safety and efficacy of drug molecules by formulating a convenient dosage form for administration and to achieve better patient compliance. One such approach was fast dissolving tablets which have gained acceptance and popularity in the recent time. Several pharmaceutical industries prepared fast dissolving tablets by direct compression technique by selecting suitable super disintegrants. Direct compression technique offers important advantages such as increased output, reduced cost, less machinery and improved drug stability compared to wet granulation method.The aim of the work is to enhance the solubility, dissolution rate and oral bioavailability of poorly soluble drugs lovastatin and simvastatin by formulating them as solid dispersions using various techniques with PEG-6000 as a carrier and subsequent preparation of fast dissolving tablets with the prepared solid dispersions using different concentrations of super disintegrants and comparing them with that of the marketed product.

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