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LAP Lambert Academic Publishing Formulation and Evaluation of an In Situ Gel for Ocular Delivery

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£42.00 £39.90 £40.74 £41.58 £42.42 £43.26 £44.10 26 July 2026 13 August 2026 31 August 2026 18 September 2026 06 October 2026
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73 days 0 18 37 55 73 £42 Days at Price

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Price levels: 1 different prices over 73 days

Description

Norfloxacin ophthalmic solution has been shown to be effective ocular infections and may be used in patients with chronic conjunctivitis or ocular irritation. Norfloxacin in-situ gel was prepared using various concentrations of polymers such as Carbopol-940 (0., 0.2, 0.3 0.4and 0.5% w/v), HPMC- E50LV (1.5 % w/v), HPMC E4M (0.6 %w/v) and HPMC K4M (0.5% w/v) by pH triggered gelling system with an objectives of increasing contact time, achieving controlled release, reduction in frequency of administration and greater therapeutic efficacy of drug. The prepared in-situ gels were then evaluated for their visual appearance, clarity, pH, drug content analysis, in-vitro gelation (Gelling capacity), rheological studies, sterility testing, textureanalysis and in-vitro drug release studies. It is evident from these studies that, formed polymeric in-situ gels had transparent, clear possessing satisfactory gelling capacity. The developed formulation was light yellow in colour, therapeutically efficacious, stable, non irritant with sustained release of drug.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
19 September 2013
Listed Since
24 October 2013

Barcode

No barcode data available

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