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LAP Lambert Academic Publishing An Efficient Pyrimidine Scaffolds against Bacterial Strains: Pyrimidine Derivatives

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£56.00 £53.20 £54.32 £55.44 £56.56 £57.68 £58.80 26 July 2026 08 August 2026 22 August 2026 05 September 2026 19 September 2026
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Description

A series of novel 2-(substituted benzylidene)-7-(4-bromophenyl)-5-(furan-2-yl)-2H-thiazolo[3,2-a]pyrimidin-3(7H)-ones were synthesized by using established methods and were characterized by IR, 1H NMR and Mass spectroscopy in order to confirm their formation. These compounds were synthesized to evaluate their antitubercular, antibacterial and antifungal potency. Docking studies revealed the importance of functional groups and its different biological action. They were found to be potent against Mycobacterium tuberculosis H37Ra strain, also potent against Gram +ve, Gram –ve and fungal strains

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