Mezenkhimal'nye stvolovye kletki pri rasseyannom skleroze: Immunosupressivnoe deystvie mezenkhimal'nykh stvolovykh kletok na T-kletochnyy otvet pri rasseyannom skleroze - Image 1

£51.00

LAP Lambert Academic Publishing Mezenkhimal'nye stvolovye kletki pri rasseyannom skleroze: Immunosupressivnoe deystvie mezenkhimal'nykh stvolovykh kletok na T-kletochnyy otvet pri rasseyannom skleroze

Name: Mezenkhimal'nye stvolovye kletki pri rasseyannom skleroze: Immunosupressivnoe deystvie mezenkhimal'nykh stvolovykh kletok na T-kletochnyy otvet pri rasseyannom skleroze
Brand: LAP Lambert Academic Publishing
Price: 51.0 GBP
Availability: InStock

Medical & Healthcare Practitioners

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Description

V dannoy knige rassmotreny immunoregulyatornye svoystva i mekhanizmy immmunosupressii mezenkhimal'nykh stvolovykh kletok (MSK) pri autoimmunnykh demieliniziruyushchikh zabolevaniyakh tsentral'noy nervnoy sistemy cheloveka i laboratornykh zhivotnykh. Pokazano, chto autologichnye i allogennye MSK rannikh passazhey v ravnoy stepeni ingibiruyut kak antigen-nespetsificheskuyu, tak i mielin-indutsirovannuyu proliferatsiyu T-kletok pamyati patsientov s rasseyannym sklerozom. Mekhanizm MSK-indutsiruemoy immunosupressii mozhet byt' svyazan s ostanovkoy kletochnogo deleniya na urovne rannikh generatsiy, snizheniem produktsii interferona-γ i povysheniem ekspressii FoxP3. Pri etom, rastvorimyy posrednik immunoregulyatornykh svoystv MSK - prostaglandin E2 konstitutivno imi ne produtsiruetsya, a trebuet parakrinnogo signala ot T-limfotsitov. Poluchennye rezul'taty pozvolyat otsenit' vozmozhnosti dal'neyshego ispol'zovaniya kul'tur MSK v kachestve kletochnogo transplantata pri patogeneticheskoy terapii rasseyannogo skleroza, usovershenstvovat' kriterii otbora patsientov i povysit' uroven' klinicheskikh i nauchnykh issledovaniy v nevrologii, immunologii, transplantologii i kletochnoy biologii.

Product Specifications

Brand: LAP Lambert Academic Publishing
Format: paperback
ASIN: 3659270342
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners
Domain: Amazon UK
Release Date: 16 November 2012
Listed Since: 07 February 2013

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LAP Lambert Academic Publishing Mezenkhimal'nye stvolovye kletki pri rasseyannom skleroze: Immunosupressivnoe deystvie mezenkhimal'nykh stvolovykh kletok na T-kletochnyy otvet pri rasseyannom skleroze

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