£76.38

Springer Clostridial Neurotoxins: The Molecular Pathogenesis of Tetanus and Botulism: 195 (Current Topics in Microbiology and Immunology, 195)

Price data last checked 48 day(s) ago - refreshing...

View at Amazon

We'll watch every seller, every day. One email when your price arrives.

It has never been this cheap. We have no record of a lower price.

£76 today · cheaper than every other day in the last 3 months

NEW HERE?

Amazon shows you one price. We show you all of them.

Tosheroon watches Amazon prices so you don't have to. Every product on Amazon has a price history — we make it visible. Set the price you'd actually pay, and we'll email you the second it gets there. No app, no account, one email.

WHAT'S ON THIS PAGE

↓ Price chart
when this has been cheap or pricey
↓ Forecast
where the price is heading next
↓ Statistics
all-time high & low, recent range
↑ Price alert
name your number, we'll email you

Price History & Forecast

Grey patches = out of stock. Cheaper = lower on the chart. Hover for exact prices.

Last 35 days · 35 data points (no recent data)

Historical
Generating forecast…
£76.38 £72.56 £74.09 £75.62 £77.14 £78.67 £80.20 01 May 2026 09 May 2026 18 May 2026 26 May 2026 04 June 2026

Price Distribution

Price distribution over 35 days • 1 price levels

Days at Price
35 days 0 9 18 26 35 £76 Days at Price

Price Analysis

Most common price: £76 (35 days, 100.0%)

Price range: £76 - £76

Price levels: 1 different prices over 35 days

Description

Tetanus has been known from the very beginning of medical literature since it was first described by Hyppocrates of Cos in the fifth century B.C. For 24 centuries it was considered a neuro logical disease until the breakthrough of CARLE and RATIONE (1884) who demonstrated its infectious etiology. Following the establishment of purified cultures of Clostridium tetani(KITASATO 1889), FABER (1890), and TIZZONI and CATIANI (1890) demon strated that the disease is actually an intoxication caused by a proteic neurotoxin. This toxin was shown by BRUSHCHETIINI (1892) to move retroaxonally and to act at the spinal cord level. Soon thereafter VAN ERMENGEN (1897) demonstrated that botu lism is also due to intoxication with a protein toxin produced by bacteria of the genus Clostridium. These bacteria and their spores and ubiquitous, and the majority of them do not produce neurotoxins. The selective advantage of producing such potent toxin is still a matter of speculation (see Popoff, this volume). The next major advance was the discovery that tetanus neurotoxin 1 can be converted by formaldehyde treatment to a nonpathogenic but still fully immunogenic form, and that this can be used successfully as a vaccine to prevent tetanus (RAMON and DESCOMBEY 1925). Similar vaccines (toxoids) can be prepared with botulism neurotoxins (see MiDDLEBROOK and BROWN, this volume). The prevention oftetanus by vaccination (see Galatzka and Gasse, this volume) is one of the great successes of basic research coupled with an efficient public medicine service.

Product Specifications

Format
paperback
Domain
Amazon UK
Publication Date
13 November 2013
Listed Since
07 November 2013

Barcode

No barcode data available

Similar Products You Might Like

Botulinum Neurotoxins: 364 (Current Topics in Microbiology and Immunology, 364)
84% match

Botulinum Neurotoxins: 364 (Current Topics in Microbiology and Immunology, 364)

Springer

£100.08 04 Jun 2026
Botulinum Toxin: Therapeutic Uses, Procedures and Efficacy (Neurology - Laboratory and Clinical Research Developments)
82% match

Botulinum Toxin: Therapeutic Uses, Procedures and Efficacy (Neurology - Laboratory and Clinical Research Developments)

£92.99 19 Jun 2026
Molecular Aspects of Botulinum Neurotoxin: 4 (Current Topics in Neurotoxicity, 4)
81% match

Molecular Aspects of Botulinum Neurotoxin: 4 (Current Topics in Neurotoxicity, 4)

Springer

£80.64 15 Jun 2026
Molecular Aspects of Botulinum Neurotoxin: 4 (Current Topics in Neurotoxicity, 4)
81% match

Molecular Aspects of Botulinum Neurotoxin: 4 (Current Topics in Neurotoxicity, 4)

Springer

£95.40 06 Jun 2026
Natural Toxins 2: Structure, Mechanism of Action, and Detection: 391 (Advances in Experimental Medicine and Biology, 391)
79% match

Natural Toxins 2: Structure, Mechanism of Action, and Detection: 391 (Advances in Experimental Medicine and Biology, 391)

Springer

£77.33 30 May 2026
ADP-Ribosylating Toxins: 175 (Current Topics in Microbiology and Immunology, 175)
78% match

ADP-Ribosylating Toxins: 175 (Current Topics in Microbiology and Immunology, 175)

Springer

£73.10 05 Jun 2026
Corynebacterium diphtheriae and Related Toxigenic Species: Genomics, Pathogenicity and Applications
77% match

Corynebacterium diphtheriae and Related Toxigenic Species: Genomics, Pathogenicity and Applications

Springer

£107.98 04 Jun 2026
Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine
77% match

Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine

Springer

£73.10 31 May 2026
Clostridium difficile: 250 (Current Topics in Microbiology and Immunology, 250)
76% match

Clostridium difficile: 250 (Current Topics in Microbiology and Immunology, 250)

Springer

£120.65 05 Jun 2026
Clostridium difficile: 250 (Current Topics in Microbiology and Immunology, 250)
76% match

Clostridium difficile: 250 (Current Topics in Microbiology and Immunology, 250)

Springer

£107.98 05 Jun 2026
Neurobrucellosis: Clinical, Diagnostic and Therapeutic Features
76% match

Neurobrucellosis: Clinical, Diagnostic and Therapeutic Features

Springer

£88.17 05 Jun 2026
Bacterial Toxins: Methods and Protocols: 145 (Methods in Molecular Biology, 145)
75% match

Bacterial Toxins: Methods and Protocols: 145 (Methods in Molecular Biology, 145)

Humana

£107.98 27 May 2026
Botulinum Toxin Treatment of Pain Disorders
75% match

Botulinum Toxin Treatment of Pain Disorders

Springer

£103.41 29 May 2026
Immunotoxin Methods and Protocols: 166 (Methods in Molecular Biology, 166)
75% match

Immunotoxin Methods and Protocols: 166 (Methods in Molecular Biology, 166)

Humana

£75.25 02 Jun 2026
Rabies: 7 (Developments in Veterinary Virology, 7)
75% match

Rabies: 7 (Developments in Veterinary Virology, 7)

Springer

£149.62 01 Jun 2026
Microorganisms and Bioterrorism (Infectious Agents and Pathogenesis)
74% match

Microorganisms and Bioterrorism (Infectious Agents and Pathogenesis)

Springer

£107.98 02 Jun 2026
Botulinum Toxin Treatment in Clinical Medicine: A Disease-Oriented Approach
74% match

Botulinum Toxin Treatment in Clinical Medicine: A Disease-Oriented Approach

Springer

£98.69 05 Jun 2026
The Molecular Biology of Photorhabdus Bacteria: 402 (Current Topics in Microbiology and Immunology, 402)
74% match

The Molecular Biology of Photorhabdus Bacteria: 402 (Current Topics in Microbiology and Immunology, 402)

Springer

£105.69 06 Jun 2026
Tuberculosis: 215 (Current Topics in Microbiology and Immunology, 215)
74% match

Tuberculosis: 215 (Current Topics in Microbiology and Immunology, 215)

Springer

£76.38 06 Jun 2026
Veterinary Vaccines: 4 (Progress in Vaccinology, 4)
74% match

Veterinary Vaccines: 4 (Progress in Vaccinology, 4)

Springer

£77.74 12 Jun 2026
Botulinum Toxin for Asians
74% match

Botulinum Toxin for Asians

Springer

£65.57 17 Jun 2026
Vaccines against Allergies: 352 (Current Topics in Microbiology and Immunology, 352)
74% match

Vaccines against Allergies: 352 (Current Topics in Microbiology and Immunology, 352)

Springer

£107.98 24 May 2026
Toxins and Drug Discovery (Toxinology)
74% match

Toxins and Drug Discovery (Toxinology)

Springer

£187.87 05 Jun 2026
Molecular Neurosurgery with Targeted Toxins
74% match

Molecular Neurosurgery with Targeted Toxins

Humana

£88.17 31 May 2026