£75.84

Springer Acute Renal Failure in the Critically Ill: 20 (Update in Intensive Care and Emergency Medicine, 20)

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£76 today · usual range £0–£0 · best ever £49

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Last 638 days • 638 data points (No recent data available)

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£79.90 £45.45 £52.96 £60.48 £68.00 £75.52 £83.03 10 June 2024 16 November 2024 24 April 2025 30 September 2025 09 March 2026

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Price distribution over 638 days • 9 price levels

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6 days 56 days 62 days 21 days 39 days 257 days · current 4 days 49 days 144 days 0 64 129 193 257 £49 £66 £67 £68 £73 £76 £78 £79 £80 Days at Price

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Most common price: £76 (257 days, 40.3%)

Price range: £49 - £80

Price levels: 9 different prices over 638 days

Description

Over the last 10 years the syndrome of severe acute renal failure has progressively changed in its epidemiology. It is now most frequently seen in critically ill patients, typically in the context of sepsis and multiorgan failure. This epidemiologic change has meant that intensive care physicians and nephrologists must now work in close cooperation at all times and must take many com plex issues of prevention, pathogenesis, and management into account that they did not previously have to tackle. Simultaneously, the last 10 years have seen the development of major technical and conceptual changes in the field of renal replacement therapy. There are now previously unavailable therapeutic options that provide physicians with a flexible and rapidly evolving armamentarium. The nutrition of these patients, previously limited by the par tial efficacy of renal replacement therapies, has also become more aggressive and more in tune with the needs of critically ill patients. Increased understanding of the pathogenesis of the multi organ failure syndrome has focused on the role of many soluble "mediators of injury" (cytokines, leukotrienes, prostanoids etc.). These molecules are likely to participate in the pathogenesis of acute renal failure. Their generation and disposal is also affected by different techniques of artificial renal support.

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