Signaling Through the Cell Matrix: 25 (Progress in Molecular and Subcellular Biology, 25) - Image 1

£74.28

Springer Signaling Through the Cell Matrix: 25 (Progress in Molecular and Subcellular Biology, 25)

Name: Signaling Through the Cell Matrix: 25 (Progress in Molecular and Subcellular Biology, 25)
Brand: Springer
Price: 74.28 GBP
Availability: InStock

Oncology

About as cheap as it gets. The only time it was cheaper was 2 years ago.

£74 today · all-time low £72 (Jun 2024) · usually the usual

NEW HERE?

Amazon shows you one price. We show you all of them.

Tosheroon watches Amazon prices so you don't have to. Every product on Amazon has a price history — we make it visible. Set the price you'd actually pay, and we'll email you the second it gets there. No app, no account, one email.

WHAT'S ON THIS PAGE

↓ Price chart
when this has been cheap or pricey

↓ Forecast
where the price is heading next

↓ Statistics
all-time high & low, recent range

↑ Price alert
name your number, we'll email you

Price History & Forecast

Grey patches = out of stock. Cheaper = lower on the chart. Hover for exact prices.

Last 638 days • 638 data points (No recent data available)

Historical

Generating forecast...

Price Distribution

Price distribution over 638 days • 2 price levels

Days at Price

Current Price

Price Analysis

Most common price: £75 (339 days, 53.1%)

Price range: £73 - £75

Price levels: 2 different prices over 638 days

Description

The genetic information contained in a cell needs the appropriate environment to express itself, not only the intracellular environment but also the extracel lular one. The latter is provided to a great extent by the molecules which constitute the extracellular matrix. On the one hand, the matrix creates inter alia the right pH and osmotic envi ronment and allows the diffusion of messengers targeting the cell membrane; on the other hand, it has a mechanical effect whose relevance began to be understood 28 years ago. Basically, the messages that reach the cell and are then transported to the genome depend on molecular conformational flexibility. Molecular structures usually prevail because they represent states of minimum potential energy cre ating energy barriers which are activated through conformational changes. From the periphery to the nucleus the information flows through the activa tion of energy barriers. The tools used to switch from low-energy to high energy molecular configurations are: the binding of ligands to their receptors, gradients of electrochemical potential created by ion pumps, Ca2+ mobiliza tion, and phosphorylation and dephosphorylation. Variation in molecular con figuration through molecular binding is in itself sufficient to trigger ion pumps and activate kinases and phosphatases. This is one aspect of the mechanical role of the extracellular matrix dealt with herein: the induction of molecular and supramolecular conformational modifications through interactions with the cell membrane, which promote the transduction and centripetal progression of signals. From the Back Cover This book covers a hot subject in cell biology; i.e. how the cell environment sends messages to the cell, regulates gene expression, and modulates the cell phenotype. For a long time the extracellular matrix was believed to have only a supporting role for cell attachement. However, it became apparent that the matrix participates actively in cell metabolism. The experiments that led to this conclusion are described in this volume. Progressively, molecules have been identified that transmit this signaling at the cell-matrix interface. Their identity and mechanism of action are also illustrated in this book. Finally, it explains the role the cell-matrix relationship plays in the regulation of cell proliferation, cell differentiation, and the expression of malignancy.

Product Specifications

Brand: Springer
Format: Paperback
ASIN: 3642641172
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Oncology
Domain: Amazon UK
Release Date: 27 September 2011
Listed Since: 12 July 2012

Barcode

No barcode data available

Springer Signaling Through the Cell Matrix: 25 (Progress in Molecular and Subcellular Biology, 25)

About as cheap as it gets. The only time it was cheaper was 2 years ago.

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

Intercellular Communication in Cancer

Evolution of Extracellular Matrix (Biology of Extracellular Matrix)

Extracellular Matrix Omics: 7 (Biology of Extracellular Matrix, 7)

Mechanobiology of Cell-Cell and Cell-Matrix Interactions

Springer Extracellular Matrix Omics: 7 - Biology of ECM Book

Extracellular Matrix Remodeling

Mimicking the Extracellular Matrix: The Intersection of Matrix Biology and Biomaterials

The Extracellular Matrix: an Overview (Biology of Extracellular Matrix)

Methods in Cell Biology,83: Volume 83

Cell Mechanics: From Single Scale-Based Models to Multiscale Modeling

The Extracellular Matrix: an Overview (Biology of Extracellular Matrix)

Cell Movement in Health and Disease

Cellular Mechanics and Biophysics: Structure and Function of Basic Cellular Components Regulating Cell Mechanics (Biological and Medical Physics, Biomedical Engineering)

Lewin's Cells

Organization of the Extracellular Matrix: A Polarization Microscopic Approach

Methods in Extracellular Matrix Biology (Volume 143) (Methods in Cell Biology, Volume 143)

Development Biology (Volume 11) (Principles of Medical Biology, Volume 11)

The Cell Surface in Signal Transduction: 12 (Nato ASI Subseries H:)

Tumor Microenvironment: Extracellular Matrix Components – Part B: 1272 (Advances in Experimental Medicine and Biology, 1272)

Metabolic Pumps and Intracellular Homeostasis, Hormones and Cell Function, Intercellular Communication, Cell Motility and Contractility, Part B ... Cell Biology. A Multi-Volume Work, Volume 5B)

Methods in Cell-Matrix Adhesion: Vol 69 (Methods in Cell Biology): Volume 69

iPSC Derived Progenitors: Volume 13 (Advances in Stem Cell Biology, Volume 13)

Methods in Cell-Matrix Adhesion (Volume 69) (Methods in Cell Biology, Volume 69)

Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease: 60 (Subcellular Biochemistry, 60)