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Springer Mitochondrial Genetics and Cancer

Amazon

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Description

This pioneering book is a unique compilation of mitochondrial genome alterations in cancer. It focuses on the emerging role of mitochondrial genome changes, bioenergetics and signaling pathways. From the Back Cover The pivotal role of mitochondrial functions in carcinogenesis is quite well established. However, the critical role of mitochondrial genome alterations to cancer development is muted in traditional textbooks. Recent scientific efforts have provided unequivocal evidence for mitochondrial genome mutations and content changes in cancer development, progression, and therapy. This pioneering book is a unique compilation of mitochondrial genome alterations in cancer. While primarily focused on the emerging role of mitochondrial genome changes, bioenergetics and signaling pathways, attention is also given to the metabolic transformations of the cancer cell, as well as the established altered cell death processes that underlie cancer evolution and treatment resistance. About the Author Gabriel D. Dakubo is the founder of Mito-Onc Consultancy, a pioneer consulting firm that provides evidence-based advice on discovery, validation and regulatory submission of cancer biomarkers based on mitochondrial genomic alterations.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
28 November 2014
Listed Since
02 December 2014

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