Neurofibromatosis Type 1: Molecular and Cellular Biology - Image 1

£93.31

Springer Neurofibromatosis Type 1: Molecular and Cellular Biology

Name: Neurofibromatosis Type 1: Molecular and Cellular Biology
Brand: Springer
Price: 93.31 GBP
Availability: InStock

Medical Genetics

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Description

Neurofibromatosis type 1 (NF1), caused by mutational inactivation of the NF1 tumour suppressor gene, is one of the most common dominantly inherited human disorders, affecting 1 in 3000 individuals worldwide. This book presents in concise fashion, but as comprehensively as possible, our current state of knowledge on the molecular genetics, molecular biology and cellular biology of this tumour predisposition syndrome. Written by internationally recognized experts in the field, the 44 chapters that constitute this edited volume provide the reader with a broad overview of the clinical features of the disease, the structure and expression of the NF1 gene, its germ line and somatic mutational spectra and genotype-phenotype relationships, the structure and function of its protein product (neurofibromin), NF1 modifying loci, the molecular pathology of NF1-associated tumours, animal models of the disease, psycho-social aspects and future prospects for therapeutic treatment.

Product Specifications

Brand: Springer
Format: hardcover
ASIN: 3642328636
Category: Books > Subjects > Scientific, Technical & Medical > Medicine & Nursing > Basic Medical Science > Medical Genetics
Domain: Amazon UK
Release Date: 30 January 2013
Listed Since: 20 July 2012

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Springer Neurofibromatosis Type 1: Molecular and Cellular Biology

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