£143.27

About as cheap as it gets — within 5% of the all-time low it hit 1 month ago.

£143 today · all-time low £141 (Sep 2026) · usually £143

Springer Cancer Immunology and Immunotherapy: 344 (Current Topics in Microbiology and Immunology, 344)

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Price History & Forecast

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Last 62 days · 62 data points (no recent data)

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£146.52 £140.31 £141.66 £143.02 £144.37 £145.73 £147.09 25 July 2026 09 August 2026 24 August 2026 08 September 2026 24 September 2026
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Price Distribution

Price distribution over 62 days • 4 price levels

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Current Price
15 days 2 days · current 40 days 5 days 0 10 20 30 40 £141 £143 £145 £147 Days at Price

Price Analysis

Most common price: £145 (40 days, 64.5%)

Price range: £141 - £147

Price levels: 4 different prices over 62 days

Description

The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.

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