£92.78

Springer Phosphodiesterases as Drug Targets: 204 (Handbook of Experimental Pharmacology, 204)

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Price History & Forecast

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Last 46 days • 46 data points (No recent data available)

Historical
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£158.40 £86.22 £101.97 £117.72 £133.46 £149.21 £164.96 19 March 2026 30 March 2026 10 April 2026 21 April 2026 03 May 2026

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Current Price
3 days · current 35 days 8 days 0 9 18 26 35 £93 £101 £158 Days at Price

Price Analysis

Most common price: £101 (35 days, 76.1%)

Price range: £93 - £158

Price levels: 3 different prices over 46 days

Description

Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that selectively target this class of enzymes. Novel characteristics of PDEs are viewed as unique opportunities to increase specificity and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts related to the design and use of PDE inhibitors.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
02 August 2011
Listed Since
22 November 2010

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