Contrast Agents I: Magnetic Resonance Imaging: 221 (Topics in Current Chemistry) - Image 1

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Springer Contrast Agents I: Magnetic Resonance Imaging: 221 (Topics in Current Chemistry)

Name: Contrast Agents I: Magnetic Resonance Imaging: 221 (Topics in Current Chemistry)
Brand: Springer
Price: 201.56 GBP
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Laboratory Medicine

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Description

Extracellular MRI and X-ray contrast agents are characterized by their phar- cokinetic behaviour.After intravascular injection their plasma-level time curve is characeterized by two phases. The agents are rapidly distributed between plasma and interstitial spaces followed by renal elimination with a terminal half-live of approximatly 1–2 hours. They are excreted via the kidneys in unchanged form by glomerular filtration. Extracellular water-soluble contrast agents to be applied for X-ray imaging were introduced into clinical practice in 1923. Since that time they have proved to be most valuable tools in diagnostics.They contain iodine as the element of choice with a sufficiently high atomic weight difference to organic tissue. As positive contrast agents their attenuation of radiation is higher compared with the attenuation of the surrounding tissue. By this contrast enhancement X-ray diagnostics could be improved dramatically. In 2,4,6-triiodobenzoic acid derivatives iodine is firmly bound. Nowadays diamides of the 2,4,6-triiodo-5-acylamino-isophthalic acid like iopromide (Ultravist, Fig. 1) are used as non-ionic (neutral) X-ray contrast agents in most cases [1].

Product Specifications

Brand: Springer
Format: paperback
ASIN: 3642075967
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Allied Health Professions > Laboratory Medicine
Domain: Amazon UK
Release Date: 15 December 2010
Listed Since: 01 October 2010

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Springer Contrast Agents I: Magnetic Resonance Imaging: 221 (Topics in Current Chemistry)

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