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Springer Genome Integrity: Facets and Perspectives: 1 (Genome Dynamics and Stability, 1)

Name: Genome Integrity: Facets and Perspectives: 1 (Genome Dynamics and Stability, 1)
Brand: Springer

Biochemistry

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Product Description This is the first book to give a full overview on genome integrity in different species. From microorganisms to humans, this volume provides an interdisciplinary overview of how genome integrity is maintained. Written by an international panel of experts, the book addresses the connection between genome integrity and human disease. From the Back Cover Cells and viruses maintain a genome capable of multiplication, variation and heredity. A genome consists of chromosomes, each being built up of two complementary strands of nucleic acid known as DNA. Its chemical integrity, however, is under constant assault from metabolic mutagens, such as hydroxy-radicals, endonucleases, radiation, replication errors, and environmental mutagens. From microorganisms to humans, this volume provides an interdisciplinary overview of how genome integrity is maintained. The volume begins with DNA replication and continues with replicative DNA repair and pleiotropic protein interactions. Examples of human diseases are included and the cellular responses to radiation and genotoxic stress affecting whole genomes are reviewed.

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Brand: Springer
Format: paperback
ASIN: 3642072267
Category: Books > Subjects > Science, Nature & Maths > Biological Sciences > Biochemistry
Domain: Amazon UK
Release Date: 25 November 2010
Listed Since: 01 October 2010

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Springer Genome Integrity: Facets and Perspectives: 1 (Genome Dynamics and Stability, 1)

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