Total Synthesis of Galbulimima Alkaloids: Himgaline and GB13 - Image 1

£66.00

VDM Verlag Total Synthesis of Galbulimima Alkaloids: Himgaline and GB13

Name: Total Synthesis of Galbulimima Alkaloids: Himgaline and GB13
Brand: VDM Verlag
Price: 66.0 GBP
Availability: InStock

Chemistry

It has never been this cheap. We have no record of a lower price.

£66 today · cheaper than every other day in the last 3 months

NEW HERE?

Amazon shows you one price. We show you all of them.

Tosheroon watches Amazon prices so you don't have to. Every product on Amazon has a price history — we make it visible. Set the price you'd actually pay, and we'll email you the second it gets there. No app, no account, one email.

WHAT'S ON THIS PAGE

↓ Price chart
when this has been cheap or pricey

↓ Forecast
where the price is heading next

↓ Statistics
all-time high & low, recent range

↑ Price alert
name your number, we'll email you

Price History & Forecast

Grey patches = out of stock. Cheaper = lower on the chart. Hover for exact prices.

Last 84 days • 84 data points (No recent data available)

Historical

Generating forecast...

Price Distribution

Price distribution over 84 days • 1 price levels

Days at Price

Price Analysis

Most common price: £66 (84 days, 100.0%)

Price range: £66 - £66

Price levels: 1 different prices over 84 days

Description

For thousands of years nature has played an important role in providing mankind with life-saving drugs. Several natural products have been clinically approved and they continue to remain as valuable medicines. However, in cases where the supply of an active natural product is limited, total synthesis is often the only means by which sufficient quantities could be generated for therapeutic use. Additionally, such a process could unveil novel pharmacophores which could serve as templates for designing new drugs. Himbacine, himgaline, and GB13 belong to a family of alkaloids isolated from the bark of a rain forest tree, Galbulimima belgraveana. While himbacine has been extensively studied for its antimuscarinic activity, the biological properties of its more complex congeners remain unexplored. This book describes total syntheses of both the enantiomers of himgaline and GB13. Key manipulations involved a Diels-Alder reaction, an aldol-type cascade cyclization, an aza-Michael reaction, and a hydroxyl-directed stereoselective ketone reduction. This synthetic achievement paves the way for future exploration of the medicinal value of compounds described herein and other related natural products.

Product Specifications

Brand: VDM Verlag
Format: paperback
ASIN: 3639004825
Category: Books > Subjects > Science, Nature & Maths > Chemistry
Domain: Amazon UK
Release Date: 18 June 2008
Listed Since: 25 June 2008

Barcode

No barcode data available

VDM Verlag Total Synthesis of Galbulimima Alkaloids: Himgaline and GB13

It has never been this cheap. We have no record of a lower price.

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

ALKALOIDS: CHEMICAL AND BIOLOGICAL PERSPECTIVES: Vol. 15: Volume 15

Molecular World: Making Modern Chemistry (Transformations: Studies in the History of Science and Technology)

Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids: 209 (Topics in Current Chemistry, 209)

Progress in the Chemistry of Organic Natural Products 107

Plant Alkaloids: A Guide to Their Discovery and Distribution

Alkaloids: 15 (Molecular Methods of Plant Analysis, 15)

Natural Products: Isolation, Structure Elucidation, History

Academic Press - The Alkaloids: Chemistry and Biology, Volume 64

Taste and Smell: 23 (Topics in Medicinal Chemistry, 23)

Taste and Smell: 23 (Topics in Medicinal Chemistry, 23)

Botanical Miracles: Chemistry of Plants That Changed the World

Total Synthesis of Indole Alkaloids: Based on Direct Construction of Pyrrolocarbazole Scaffolds via Gold-Catalyzed Cascade Cyclizations (Springer Theses)

Chemistry and Biology: 55 (The Alkaloids): Volume 55

New Light on Alkaloid Biosynthesis and Future Prospects (Volume 68) (Advances in Botanical Research, Volume 68)

The Way of Synthesis: Evolution of Design and Methods for Natural Products

Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids: 209 (Topics in Current Chemistry, 209)

The Alkaloids, Volume 66: Chemistry and Biology

The Alkaloids: Chemistry and Biology: 63: Volume 63 (The Alkaloids, Volume 63)

The Alkaloids: Chemistry and Biology: 62: Volume 62 (The Alkaloids, Volume 62)

Wiley Medicinal Chemistry of Plant-Derived Natural Products

Chemistry and Pharmacology: 48 (The Alkaloids): Volume 48

Elsevier Alkaloids: Chemistry, Biology, Ecology, and Applications

Carbohydrates as Drugs: 12 (Topics in Medicinal Chemistry, 12)

Secondary Plant Products: A Comprehensive Treatise (Volume 7) (Biochemistry of Plants, Volume 7)