Form and Function of Mammalian Lung: Analysis by Scientific Computing: 145 (Advances in Anatomy, Embryology and Cell Biology, 145) - Image 1

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Springer Form and Function of Mammalian Lung: Analysis by Scientific Computing: 145 (Advances in Anatomy, Embryology and Cell Biology, 145)

Name: Form and Function of Mammalian Lung: Analysis by Scientific Computing: 145 (Advances in Anatomy, Embryology and Cell Biology, 145)
Brand: Springer
Price: 61.1 GBP
Availability: InStock

Computer Science

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Description

1.1 Overview The precise knowledge of the three-dimensional (3-D) assembly of biological structures is still in its origin. As an example, a widely accepted concept and common belief of the structure of the airway network oflung is that of a regular, dichotomous branching pattern, also known as the trumpet model. This model, first introduced by Weibel in 1963, is often used in clinical and physiological applications. However, if this concept of dichotomy is used to model lung, a shape is obtained that is quite different from a real lung. As a matter of fact, many previous quantitative morphological and stereological investigations of lung did not concentrate on the spatial aspect of lung morphology but delivered data in a more statistical fashion. Accordingly, the functional behavior predicted by such a model becomes questionable and indeed, the morphometrically predicted lung capacity exceeds the physiological required capacity by a factor of 1.3 up to a factor of2. This problem has also been termed a paradox, as discussed by Weibel in 1983. In the rare cases where descriptive models of the mammalian bronchial tree exist, monopodial in small mammals, dichotomous in larger ones, the understanding of the historical and/or functional reasons for size-related changes in the general design is not explainable. This investigation is trying to overcome this gap by computer modeling and functional simulation.

Product Specifications

Brand: Springer
Format: paperback
ASIN: 3540644946
Category: Books > Subjects > Computing & Internet > Computer Science
Domain: Amazon UK
Release Date: 01 January 1998
Listed Since: 10 December 2006

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Springer Form and Function of Mammalian Lung: Analysis by Scientific Computing: 145 (Advances in Anatomy, Embryology and Cell Biology, 145)

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