Peptides in Oncology III: Somatostatin and LH-RH Analogues: 153 (Recent Results in Cancer Research, 153) - Image 1

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Springer Peptides in Oncology III: Somatostatin and LH-RH Analogues: 153 (Recent Results in Cancer Research, 153)

Name: Peptides in Oncology III: Somatostatin and LH-RH Analogues: 153 (Recent Results in Cancer Research, 153)
Brand: Springer
Price: 40.52 GBP
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Living with Cancer & Other Illnesses

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Description

Interference with protein-mediated intra- and intercellular pathways has become a major goal of preclinical and clinical research. A ,rapidly increasing numBer of peptides are known to be responsible for endo-, para-and autocrine sig- nal transduction. These peptides and their receptors have been studied with regard to their cell growth stimulatory ac- tion and their impact on differentiation. In parallel, peptide antagonists are being investigated in terms of their potential role in preclinical and clinical application. Thus, biotherapy might improve the clinical outcome of patients with tumors that respond to the respective hormonal manipulation. Among the numerous peptides of interest somatostatin (somatotropin release inhibitory factor) and the luteinizing hormone releasing hormone (LH-RH) have been the topic of intensive research during recent years. In this third vol- ume of peptides in oncology, experts in the field exten- sively review and update the mechanisms of action of so- matostatin and LH -RH -analogues in oncology. Somatostatin and its various short-and long-acting ana- logues have the unique feature of suppressing and inhibit- ing a wide range of cellular processes including cell prolif- eration. Receptors for these peptides which belong to the family of neuropeptides or neurotransmitters, are widely distributed, a feature which is not in keeping with the gen- eral view of a growth hormone regulatory system. LH -RH analogues play an established role in curative (adjuvant) and palliative treatment of hormone sensitive tumors.

Product Specifications

Brand: Springer
Format: hardcover
ASIN: 3540644296
Category: Books > Subjects > Biography > Social & Health Issues > Living with Cancer & Other Illnesses
Domain: Amazon UK
Release Date: 12 November 1999
Listed Since: 16 December 2006

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Springer Peptides in Oncology III: Somatostatin and LH-RH Analogues: 153 (Recent Results in Cancer Research, 153)

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