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Springer Ein Jahrhundert endokrine Therapie des Mammakarzinoms: Von Beatson bis heute

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Description

Die hormonelle Therapie hat seit langer Zeit einen festen Stellenwert in der Behandlung des Mammakarzinoms. 1m Juni 1895 ftihrte der schottische Chirurg Beatson die erste Ovarektomie als therapeuti- sche MaBnahme bei einer Patientin mit lokal fortgeschrittenem Mammakarzinom durch, welche durch eine Operation an der Brust allein nicht mehr sinnvoll zu behandeln war. Aus AniaB dieser historischen Pioniertat initiierte ZENECA, als weltweit forschendes Unternehmen auf dem Gebiet der hormo- nellen Krebstherapie, genau 100 Jahre spater ein wissenschaftliches Symposium zum Thema ,,100 Jahre Endokrine Therapie des Mam- makarzinoms" in Heidelberg. Die dort eingeladenen Autoren zeigen im folgenden die histo- rische Entwicklung von Diagnostik und Therapie des Mammakarzi- noms unter besonderer Berticksichtigung endokriner MaBnahmen auf. Ein weiterer Schwerpunkt sind die aktuellen Aspekte auf dem Gebiet der Grundlagenforschung der adjuvanten und palliativen Hormontherapie. Heute gelten endokrine Regulationsmechanismen und darauf basierende Therapieschritte als die wesentlichen Fortschritte der Brustkrebsbehandlung. Die Entwicklung der letzten 100 Jahre hat gezeigt, daB heute alle ursprtinglich durchgeftihrten chirurgischen Manipulationen durch Hormongaben ersetzt werden k6nnen. Die Herausgeber hoffen, daB in Zukunft vermehrt Aspekte der Pravention und Frtiherkennung in die klinische Entwicklung mit- einbezogen werden.

Product Specifications

Format
Paperback
Domain
Amazon UK
Release Date
09 October 1996
Listed Since
21 February 2011

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