Leucocyte Trafficking: The Role of Fucosyltransferases and Selectins: 44 (Ernst Schering Foundation Symposium Proceedings, 44) - Image 1

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Springer Leucocyte Trafficking: The Role of Fucosyltransferases and Selectins: 44 (Ernst Schering Foundation Symposium Proceedings, 44)

Name: Leucocyte Trafficking: The Role of Fucosyltransferases and Selectins: 44 (Ernst Schering Foundation Symposium Proceedings, 44)
Brand: Springer
Price: 113.27 GBP
Availability: InStock

General Medical Issues

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Description

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

Product Specifications

Brand: Springer
Format: hardcover
ASIN: 3540401121
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > General Medical Issues
Domain: Amazon UK
Release Date: 07 October 2003
Listed Since: 22 December 2006

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Springer Leucocyte Trafficking: The Role of Fucosyltransferases and Selectins: 44 (Ernst Schering Foundation Symposium Proceedings, 44)

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