£385.84

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£386 today · previous high £386 · all-time low £110

Springer Cannabinoids: 168 (Handbook of Experimental Pharmacology, 168)

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£385.84 £82.42 £148.62 £214.82 £281.02 £347.22 £413.42 16 August 2026 03 September 2026 22 September 2026 10 October 2026 29 October 2026
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Description
Less than 20 years ago the ?eld of cannabis and the cannabinoids was still c- sidered a minor, somewhat quaint, area of research. A few groups were active in the ?eld, but it was already being viewed as stagnating. The chemistry of cannabis 9 9 was well known, ? -tetrahydrocannabinol (? -THC), identi?ed in 1964, being the only major psychoactive constituent and cannabidiol, which is not psychoactive, possibly contributing to some of the effects. These cannabinoids and several s- thetic analogs had been thoroughly investigated for their pharmacological effects. Their mode of action was considered to be non-speci?c. The reasons for this - sumption were both technical and conceptual. On the technical side, it had been shown that THC was active in both enantiomeric forms (though with a different level of potency) and this observation was incompatible with action on biological substrates―a receptor, an enzyme, an ion channel―which react with a single stereoisomer only. The conceptual problem related to THC activity. This had been pointed out by several highly regarded research groups that had shown that many of the effects seen with cannabinoids were related to those of biologically active lipophiles, and that many of the effects of THC, particularly chronic ones, were comparable to those seen with anaesthetics and solvents.

Product Specifications
Brand
Springer
Format
hardcover
ASIN
354022565X
Category
Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Neurology & Clinical Neurophysiology
Domain
Amazon UK
Release Date
21 March 2005
Listed Since
10 December 2006

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No barcode data available

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