Springer Descent of the Testis

This book provides a state of the art overview of all aspects of testicular descent and cryptorchidism, including the mechanisms of descent and the causes, consequences, diagnosis, and treatment of undescended testis. The advances in understanding that have been achieved over the past two decades are clearly explained, covering the latest genetic information on the causes of normal and abnormal testicular descent, the role of INSL3 in transabdominal migration, and the evidence that a neurotransmitter released from the genitofemoral nerve mediates androgenic control of inguinoscrotal descent. Exciting changes in the management of both congenital and acquired cryptorchidism, such as the widespread use of laparoscopy for impalpable testes inside the abdominal cavity, are fully described. Evidence for the benefits of orchidopexy within the first year of life is reviewed, and an individual chapter is also devoted to hormonal treatment. Throughout the book due attention is given to ongoing controversies and divergences of opinion. This new edition of Descent of the Testis will be a timely update and valuable reference for all who are involved in research into testicular descent and management of cryptorchidism. Review “This new edition of the book presents a clearly written overview of all aspects of testicular descent, of cryptorchidism and its possible consequences. … Each section is highly illustrated and well referenced. For pediatric endocrinologists and surgeons.” (Pediatric Endocrinology Reviews, Vol. 13 (4), June, 2016) “This slim volume attempts to present all that is currently known about the descent of the human testis and what problems of maldescent create as far as anatomical or physiological abnormalities of size, function, or location. … This can be useful to students, house officers, and attending surgeons. … This book will answer most any question about this topic. This updated edition will probably serve admirably as a standard reference for some years to come.” (Robert M. Arensman, Doody's Book Reviews, March, 2016) From the Back Cover This book provides a state of the art overview of all aspects of testicular descent and cryptorchidism, including the mechanisms of descent and the causes, consequences, diagnosis, and treatment of undescended testis. The advances in understanding that have been achieved over the past two decades are clearly explained, covering the latest genetic information on the causes of normal and abnormal testicular descent, the role of INSL3 in transabdominal migration, and the evidence that a neurotransmitter released from the genitofemoral nerve mediates androgenic control of inguinoscrotal descent. Exciting changes in the management of both congenital and acquired cryptorchidism, such as the widespread use of laparoscopy for impalpable testes inside the abdominal cavity, are fully described. Evidence for the benefits of orchidopexy within the first year of life is reviewed, and an individual chapter is also devoted to hormonal treatment. Throughout the book due attention is given to ongoing controversies and divergences of opinion. This new edition of Descent of the Testis will be a timely update and valuable reference for all who are involved in research into testicular descent and management of cryptorchidism. About the Author John M. Hutson, MD, DSc, has been Chair of Paediatric Surgery in the Department of Paediatrics, University of Melbourne, Australia since 2006 and is a former Director of General Surgery at the Royal Children’s Hospital, Melbourne. Dr. Hutson has extensive clinical and research experience and has been the recipient of many awards during a career spanning four decades, including the Royal Australasian College of Surgeons Research Prize (2006), the Coe Medal from the Pacific Association of Pediatric Surgeons (2007), and the Sir Denis Browne Medal from the British Association of Paediatric Surgeons (2008). In 2004 Dr. Hutson accepted