Resistance of Cancer Cells to CTL-Mediated Immunotherapy: 7 (Resistance to Targeted Anti-Cancer Therapeutics, 7) - Image 1

£76.41

Springer Resistance of Cancer Cells to CTL-Mediated Immunotherapy: 7 (Resistance to Targeted Anti-Cancer Therapeutics, 7)

Name: Resistance of Cancer Cells to CTL-Mediated Immunotherapy: 7 (Resistance to Targeted Anti-Cancer Therapeutics, 7)
Brand: Springer
Price: 76.41 GBP
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Diseases & Disorders

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Description

This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, proteasome inhibitors, Bcl-2 family inhibitors, PARP, antibodies, and more.

Product Specifications

Brand: Springer
Format: hardcover
ASIN: 3319178067
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders
Domain: Amazon UK
Release Date: 30 June 2015
Listed Since: 12 March 2015

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Springer Resistance of Cancer Cells to CTL-Mediated Immunotherapy: 7 (Resistance to Targeted Anti-Cancer Therapeutics, 7)

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