£162.72

About as cheap as it gets — within 5% of the all-time low it hit 1 month ago.

£163 today · all-time low £161 (Sep 2026) · usually £162

Springer Protein Expression in Down Syndrome Brain (Springer Medicine)

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£177.59 £158.98 £163.04 £167.10 £171.16 £175.22 £179.28 28 July 2026 17 August 2026 07 September 2026 28 September 2026 19 October 2026
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28 days 14 days · current 38 days 4 days 0 10 19 29 38 £161 £163 £177 £178 Days at Price

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Most common price: £177 (38 days, 45.2%)

Price range: £161 - £178

Price levels: 4 different prices over 84 days

Description

This book presents latest original research work and current opinions on Down syndrome, focussing on the molecular biology of the Down syndrome brain at the protein level, rather than at nucleic acid level, as it is the proteins that do the work, and there is a long and unpredictable way from RNA to protein. The studies used fetal brains with Down syndrome in which no neurodegeneration was found and characterized proteins by two-dimensional gel electrophoresis and mass spectrometry. The book provides new aspects, such as that neuronal density and neurotransmission is unchanged in early life but synaptosomal structures and dendritic spines are already seriously affected at the early second trimester. The presentation of a series of tentative mechanisms for the development of the Down syndrome neurophenotype provides models for present and future thinking on the neurobiology of the Down syndrome brain.

Key Features

Used Book in Good Condition

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
15 October 2001
Listed Since
08 December 2006

Barcode

No barcode data available

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