Protein Expression in Down Syndrome Brain (Springer Medicine) - Image 1

£175.71

Springer Protein Expression in Down Syndrome Brain (Springer Medicine)

Name: Protein Expression in Down Syndrome Brain (Springer Medicine)
Brand: Springer
Price: 175.71 GBP
Availability: InStock

Neurology & Clinical Neurophysiology

This is the most expensive it has ever been. Walk away.

£176 today · previous high £176 · all-time low £175

NEW HERE?

Amazon shows you one price. We show you all of them.

Tosheroon watches Amazon prices so you don't have to. Every product on Amazon has a price history — we make it visible. Set the price you'd actually pay, and we'll email you the second it gets there. No app, no account, one email.

WHAT'S ON THIS PAGE

↓ Price chart
when this has been cheap or pricey

↓ Forecast
where the price is heading next

↓ Statistics
all-time high & low, recent range

↑ Price alert
name your number, we'll email you

Price History & Forecast

Grey patches = out of stock. Cheaper = lower on the chart. Hover for exact prices.

Last 61 days • 61 data points (No recent data available)

Historical

Generating forecast...

Price Distribution

Price distribution over 61 days • 2 price levels

Days at Price

Current Price

Price Analysis

Most common price: £175 (48 days, 78.7%)

Price range: £175 - £176

Price levels: 2 different prices over 61 days

Description

When we worked on Down Syndrome brain in the past we have been focus ing on adult brain. This was a major step forwards as most work on Down Syndrome was carried out on fibroblasts or other tissues and, moreover, we introduced proteomics to identify and quantify brain protein expression. We considered evaluation of brain protein expression in Down Syndrome brain by and by more important than gene hunting at the nucleic acid level realiz ing the long unpredictable way from RNA to protein. The availability of fetal samples along with the proteomic appproach stimulated and reinforced studies on Down Syndrome brain. And indeed, it was found out that some observations on aberrant protein expression in adult Down Syndrome brain could not be verified in the fetal samples indi cating that neurodegeneration in adult Down Syndrome brain may have been responsible rather than trisomy 21. Using brains from the early second trimester of gestation led to the generation of a series of clues for the under standing of aberrant wiring of the brain in Down Syndrome and enabled the determination of altered key functions in early life; e. g. undetectably low drebrin was observed in Down Syndrome cortex, an integral constituent and marker for dendritic spines, main effectors of cross-talk between neurons. In addition, evaluation of the nature of the neuronal deficits in terms of neuro transmission markers could be established as well as neuronal density in fetal Down Syndrome cortex.

Key Features

Used Book in Good Condition

Product Specifications

Brand: Springer
Format: hardcover
ASIN: 3211837329
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Neurology & Clinical Neurophysiology
Domain: Amazon UK
Release Date: 15 October 2001
Listed Since: 08 December 2006

Barcode

No barcode data available

Springer Protein Expression in Down Syndrome Brain (Springer Medicine)

This is the most expensive it has ever been. Walk away.

Price History & Forecast

Price Distribution

Price Analysis

Description

Key Features

Product Specifications

Barcode

Similar Products You Might Like

The Molecular Biology of Down Syndrome: 57 (Journal of Neural Transmission. Supplementa, 57)

Down Syndrome: From Understanding the Neurobiology to Therapy (Volume 197) (Progress in Brain Research, Volume 197)

DOWN SYNDROME BEYOND THE INTEL: Persons with their Own Emotional World (Genetics-research and Issues)

Neurocognitive Rehabilitation of Down Syndrome: Early Years (Cambridge Medicine (Paperback))

Advances in Down Syndrome Research: 67 (Journal of Neural Transmission. Supplementa, 67)

Pediatric Neuropsychology, Third Edition: Research, Theory, and Practice

Preclinical Research in Down Syndrome: Insights for Pathophysiology and Treatments (Volume 251) (Progress in Brain Research, Volume 251)

The Oxford Handbook of Down Syndrome and Development (OXFORD LIBRARY OF PSYCHOLOGY SERIES)

Children with Down Syndrome: A Developmental Perspective

DOWN SYNDROME & DEMENTIA: A Comprehensive & Historical Review (Disability Studies)

Down Syndrome: A Review of Current Knowlegde

The Genetics of Neurodevelopmental Disorders

Down Syndrome Across the Life Span

Neurodevelopmental Disorders (SAGE Library in Developmental Psychology)

Adult with Down Syndrome: A New Challenge for Society

Cognitive & Social Skills in Neurodevelopmental Disorders

State of the Art of Research on Down Syndrome: Volume 56 (International Review of Research in Developmental Disabilities, Volume 56)

Treatment of Neurodevelopmental Disorders: Targeting Neurobiological Mechanisms

Working With Hannah: A Special Girl in a Mainstream School

Physical Health of Adults with Intellectual and Developmental Disabilities

Psychology Press - Atypical Cognitive Deficits in Disorders

Current Issues in Developmental Disorders (Current Issues in Developmental Psychology)

Educating Learners with Down Syndrome: Research, theory, and practice with children and adolescents

The Neurobiology of Aging and Alzheimer Disease in Down Syndrome