Tosheroon watches Amazon prices so you don't have to. Every product on Amazon has a price history — we make it visible. Set the price you'd actually pay, and we'll email you the second it gets there. No app, no account, one email.

WHAT'S ON THIS PAGE

↑ Price chart
when this has been cheap or pricey

↑ Forecast
where the price is heading next

↓ Statistics
all-time high & low, recent range

↑ Price alert
name your number, we'll email you

Price Distribution

Price distribution over 80 days • 2 price levels

Days at Price

Current Price

Price Analysis

Most common price: £44 (78 days, 97.5%)

Price range: £43 - £44

Price levels: 2 different prices over 80 days

Description

Summary of Genes. Thirty years ago, the gene responsible for cystic fibrosis (CF), a recessive genetic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator gene, was identified. This progress has considerably changed our understanding of the pathophysiology of CF and has paved the way for the development of novel and specific therapies for the disease. The CFTR gene contains 27 exons and is characterized by a frequent three base pair deletion of the p.Phe508del. As a result of collaborative work, today more than 2000 mutations have been reported in the gene, and their impact on protein function is now more evident and useful in designing new strategies to correct the gene defect. The field of gene therapy, as illustrated by Ziying Yan in this book, has worked on identifying an efficient vector system for the delivery of the wild-type CFTR gene to the lung. At the same time, animal models have been developed in mice, rats, rabbits, zebrafish, ferrets, and pigs to establish the efficacity of gene delivery. These animals are also of the utmost importance in testing new molecules as modulators or correctors to improve the CFTR lung function. During the last three decades, the epidemiology of CF has dramatically changed, as today cystic fibrosis is now a chronic adult pulmonary disease.

Product Specifications

Format: hardcover
ASIN: 303943683X
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners
Domain: Amazon UK
Release Date: 11 December 2020
Listed Since: 16 December 2020

Barcode

No barcode data available

It has never been this cheap. We have no record of a lower price.

Molecular Basis and Gene Therapies of Cystic Fibrosis

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

Cystic Fibrosis Diagnosis and Protocols Volume I - Research Methods

Hodson and Geddes' Cystic Fibrosis

Cystic Fibrosis Methods and Protocols Volume 70 - Research Guide

Defects of Secretion in Cystic Fibrosis: 558 (Advances in Experimental Medicine and Biology, 558)

Defects of Secretion in Cystic Fibrosis

In the Shadow of Illness: Parents and Siblings of the Chronically Ill Child

The Birth of a Genetics Policy: Social Issues of Newborn Screening

Cystic Fibrosis: Multi-Organ System Approach - Medical Reference

Molecular Genetics of Human Inherited Disease (Molecular Medical Science Series)

Molecular Pharmacology: From DNA to Drug Discovery

Cystic Fibrosis: 242 (Lung Biology in Health and Disease)

Molecular Pharmacology: From DNA to Drug Discovery

Cystic Fibrosis: Etiology, Diagnosis and Treatments - Medical Reference

Diet and Exercise in Cystic Fibrosis

Cystic Fibrosis (Lung Biology in Health and Disease)

Nutrition in Cystic Fibrosis: A Guide for Clinicians (Nutrition and Health)

Handbook of Clinical Adult Genetics and Genomics - Practice Guide

Academic Press Genomics of Rare Diseases Textbook

Gene-Based Therapeutics for Inherited Disorders - Safety & Efficacy

Genes And Disease Set, 10-Volumes

Cystic Fibrosis Care: A Practical Guide

Elsevier Chromosome 22q11.2 Deletion Syndrome Medical Book

Essentials of Medical Genetics

Gene Correction: Methods and Protocols: 1114 (Methods in Molecular Biology, 1114)

It has never been this cheap. We have no record of a lower price.

Molecular Basis and Gene Therapies of Cystic Fibrosis

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

Cystic Fibrosis Diagnosis and Protocols Volume I - Research Methods

Hodson and Geddes' Cystic Fibrosis

Cystic Fibrosis Methods and Protocols Volume 70 - Research Guide

Defects of Secretion in Cystic Fibrosis: 558 (Advances in Experimental Medicine and Biology, 558)

Defects of Secretion in Cystic Fibrosis

In the Shadow of Illness: Parents and Siblings of the Chronically Ill Child

The Birth of a Genetics Policy: Social Issues of Newborn Screening

Cystic Fibrosis: Multi-Organ System Approach - Medical Reference

Molecular Genetics of Human Inherited Disease (Molecular Medical Science Series)

Molecular Pharmacology: From DNA to Drug Discovery

Cystic Fibrosis: 242 (Lung Biology in Health and Disease)

Molecular Pharmacology: From DNA to Drug Discovery

Cystic Fibrosis: Etiology, Diagnosis and Treatments - Medical Reference

Diet and Exercise in Cystic Fibrosis

Cystic Fibrosis (Lung Biology in Health and Disease)

Nutrition in Cystic Fibrosis: A Guide for Clinicians (Nutrition and Health)

Handbook of Clinical Adult Genetics and Genomics - Practice Guide

Academic Press Genomics of Rare Diseases Textbook

Gene-Based Therapeutics for Inherited Disorders - Safety & Efficacy

Genes And Disease Set, 10-Volumes

Cystic Fibrosis Care: A Practical Guide

Elsevier Chromosome 22q11.2 Deletion Syndrome Medical Book

Essentials of Medical Genetics

Gene Correction: Methods and Protocols: 1114 (Methods in Molecular Biology, 1114)