Springer Signposts to Chiral Drugs: Organic Synthesis in Action

Written by authors with decades of experience in teaching and industrial research, this book details 15 chiral structures present in drug therapies and shares with readers the journey from synthetic biological reactions to subsequent medicinal applications. Review From the reviews: “In this timely book, Šunjić and Parnham provide an exciting selection of major achievements in drug development and unfold 15 intriguing success stories of aliskiren, vancomycin, paclitaxel, menthol, efavirenz, and others from the perspective of a medicinal chemist. … This book will be most appealing to undergraduate and graduate students with an interest in synthesis and stereochemistry … . it should be considered an instructive teaching supplement that underscores the general significance and impact of creative synthetic chemistry and stimulates further discussion in the classroom.” (Christian Wolf, Journal of the American Chemical Society, September, 2011) “The subject of the book are chiral drugs. … Each chapter can be read separately and consists of an abstract, introduction, the main part with the synthetic approach to a certain drug, conclusion and references. … References are relevant and up-to date. A long list of abbreviations and acronyms is provided at the beginning … . The book will be very useful to synthetic organic and medicinal chemists in innovative pharmaceutical companies and to scientists and ambitious students of chemistry and pharmacy.” (Branka Zorc, Acta Pharmaceutica, Vol. 61, 2011) “This … volume will be of interest to those working in synthetic organic chemistry, particularly in the medicinal chemistry area, and having as their aim the discovery of new drug entities for the pharmaceutical industries. … there is also a useful summary of synthetic methods and concepts that are developed in the individual chapters, together with a useful index. The standard of presentation is very high, with many clearly presented reaction schemes, and each chapter has a comprehensive list of references to the specific area.” (D. W. Allen, Inflammopharmacology, Vol. 19, 2011)