Elsevier Advanced Wound Repair Therapies (Woodhead Publishing Series in Biomaterials)

Wound repair is an important and lucrative sector of the medical industry. Consequently significant and increasingly sophisticated biomaterials and strategies are continuously being developed. Advanced wound repair therapies provides readers with up-to-date information on fundamental, emerging and cutting-edge biomaterials concerned with healing internal and external surgical and traumatic wounds. Part one provides readers with an introduction to chronic wounds. Part two analyses therapies for chronic wounds. Chapters in part three discuss molecular therapies for chronic wounds whilst part four reviews biologically-derived and cell-based therapies for chronic wounds. The final group of chapters cover physical stimulation therapies for chronic wounds. Key Features: provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds; chapters include the role of micro-organisms and biofilms in dysfunctional wound healing, tissue-biomaterial interaction and electrical stimulation for wound healing; covers biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair. Contents: Part 1 Introduction to chronic wounds: Dysfunctional wound healing in chronic wounds; The role of micro-organisms and biofilms in dysfunctional wound healing; Scarring and scarless wound healing; The discovery and development of new therapeutic treatments for the improvement of scarring; Monitoring chronic wounds and determining treatment. Part 2 Biomaterial therapies for chronic wounds: Functional requirements of wound repair biomaterials; Tissue-biomaterial interaction; Polymeric materials for chronic wound and burn dressings; Dry wound healing concept using spray-on dressing for chronic wounds; Assessing the effectiveness of antimicrobial wound dressings in vitro; Adhesives and interfacial phenomena in wound healing; Wound healing studies and interfacial phenomena: Use and relevance of the corneal model; Sulphonated biomaterials as glycosaminoglycan mimics in wound healing. Part 3 Molecular therapies for chronic wounds: Drug delivery dressings; Molecular and gene therapies for wound repair; Antimicrobial dressings; Avotermin: emerging evidence of efficacy for the improvement of scarring. Part 4 Biologically-derived and cell-based therapies for chronic wounds: Engineered tissues for wound repair; Commercialisation of engineered tissue products; Biologically derived scaffolds; Stem cell therapies for wound repair. Part 5 Physical stimulation therapies for chronic wounds: Electrical stimulation for wound healing; Negative pressure wound therapy; Debridement methods of non-viable tissue in wounds.