IntechOpen Mesenchymal Stem Cells - Biology, Therapeutics, and Beyond (Biochemistry)

Mesenchymal stem cells (MSCs) are among the most promising foundations of modern regenerative medicine. Endowed with a remarkable capacity for self-renewal, differentiation, and immune system modulation, these cells play an essential role in tissue repair processes, cell-based therapies, and the development of advanced biotechnological products. The growing scientific and clinical interest in MSCs reflects not only their therapeutic potential but also the diversity of fields in which they are applied, from cell and molecular biology to tissue engineering, gene therapy, oncology, and neurosciences. A deeper understanding of their mechanisms of action and interactions with the cellular microenvironment has driven the development of new translational medicine strategies aimed at regeneration and the treatment of complex diseases. The book Mesenchymal Stem Cells – Biology, Therapeutics, and Beyond brings together contributions from researchers across different specialties, exploring topics ranging from genetic engineering and genome editing to clinical and preclinical applications in regenerative medicine, neuroprotection, immunomodulation, and the use of extracellular vesicles. This diversity of perspectives highlights the multidisciplinary and constantly evolving nature of MSC research, as well as its increasing impact on contemporary biomedicine. With a comprehensive approach, this book provides an integrated view of the biology and therapeutic potential of MSCs, serving as an essential theoretical and practical resource for researchers, clinicians, and students interested in this rapidly expanding field.