Tyrosine Kinases as Druggable Targets in Cancer - Image 1

£118.98

IntechOpen Tyrosine Kinases as Druggable Targets in Cancer

Name: Tyrosine Kinases as Druggable Targets in Cancer
Brand: IntechOpen
Price: 118.98 GBP
Availability: InStock

Oncology

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Description

Protein tyrosine kinase (PTK) deregulation contributes to growth of cancer and many other diseases. The development of small-molecule tyrosine kinase inhibitors (TKIs) that target the deregulated PTKs, such as epidermal growth factor receptor (EGFR) in non-small-cell lung cancer (NSCLC) and Bcr-ABL in chronic myeloid leukemia (CML), has revolutionized disease management. In this book, we examine a few aspects of PTKs and cancer, considering efficacy, predictive markers to therapeutic response, limitations, and future directions in TKI treatment. In this rapidly evolving field, overcoming therapeutic resistance is most challenging, and multi-targeting directs the next-generation TKIs and combination therapy as ongoing strategies in cancer treatment.

Product Specifications

Brand: IntechOpen
Format: hardcover
ASIN: 1789848083
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Oncology
Domain: Amazon UK
Release Date: 25 September 2019
Listed Since: 28 April 2020

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IntechOpen Tyrosine Kinases as Druggable Targets in Cancer

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