£119.00

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£119 today · cheaper than every other day in the last 3 months

IntechOpen Human Skin Cancers - Pathways, Mechanisms, Targets and Treatments

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Last 55 days · 55 data points (no recent data)

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£119.00 £113.05 £115.43 £117.81 £120.19 £122.57 £124.95 01 August 2026 14 August 2026 28 August 2026 10 September 2026 24 September 2026
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55 days 0 14 28 41 55 £119 Days at Price

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Most common price: £119 (55 days, 100.0%)

Price range: £119 - £119

Price levels: 1 different prices over 55 days

Description
Human skin cancers, the most common type of tumors, represent a significant health burden. The deadliest is unquestionably melanoma. Half of melanomas have an activating mutation in the BRAF gene, prompting development of novel drugs, vemurafenib and dabrafenib, specifically targeting mutated BRAF. Trametinib and cobimetinib, which block MEK, a BRAF effector protein, have been used in combination with BRAF inhibitors. A promising new melanoma treatment is immunotherapy, approach that boosts patient's own immune system to attack cancer. Pembrolizumab and nivolumab inhibit PD-1, whereas Ipilimumab targets CTLA-4, another immunity check point, to boost the immune response. Here we focus on pathways, mechanisms, targets and treatments of human skin cancers, with particular emphasis on the new developments in the research on melanomas.

Product Specifications
Brand
IntechOpen
Format
hardcover
ASIN
1789230942
Category
Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Oncology
Domain
Amazon UK
Release Date
02 May 2018
Listed Since
01 May 2018

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