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Inflammasomes: Mechanism of Action, Regulation & Role in Disease

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£78.99 £75.04 £76.62 £78.20 £79.78 £81.36 £82.94 25 July 2026 05 August 2026 17 August 2026 28 August 2026 09 September 2026
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Description

The term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL-1β takes place. Inflammasome regulation is critical for the maintenance of homeostasis: an imbalance in this fine-tuning is responsible for the establishment of infectious, autoimmune, metabolic and neurodegenerative diseases. This book examines the activation and function of inflammasomes during fungal infections; inflammasome involvement in carcinogenesis; and the role of inflammasomes in protozoan infections.

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