Humana Genomics in Endocrinology: DNA Microarray Analysis in Endocrine Health and Disease (Contemporary Endocrinology)

Genomics in Endocrinology focuses on exciting new advances in endocrinology resulting from DNA microarray studies and includes a comprehensive introduction to the use of DNA microarrays in endocrinology. The text provides the basis for further understanding of the usefulness of microarray analyses in endocrinology research. Topics discussed include the methodology of DNA microarrays and general methods for the analysis of microarray data. Review From the reviews: "This book is intended to introduce endocrinologists to the field of genomic analysis including both wet-bench and downstream analysis/interpretation. The work is nicely broken into application areas by field of endocrinology and therefore presents the material in a way that should be interesting to readers and applicable to their particular questions. … The material is presented across several levels and therefore different portions should be of use to trainees, starting at the graduate level, through experienced principal investigators. … a good addition to the canon." (Gene C Webb, Doody’s Review Service, March, 2008) "This book is aimed to bridge between the advanced knowledge acquired by new technologies in genetics and endocrinology, such as the use of microarrays. … For geneticists and endocrinologists." (Pediatric Endocrinology Reviews, Vol. 5 (4), June, 2008) “Contemporary Endocrinology series provides the necessary insight into DNA microarray technology and some of its applications in endocrinology, serving as a critical guide to scientists using the technology, as well as a primary source of information for the clinical endocrinologists, about the results obtained to date. … This volume is an indispensable guide to the new and exciting world of genome-wide transcription analysis and its applications in endocrinology.” (Serban Radian, Acta Endocrinologica, Vol. 1, 2009) From the Back Cover In recent years, the development of new technologies capable of monitoring genome function has resulted in fewer hopeful estimates and increasingly solid depictions of genome output from individual samples. Genomics in Endocrinology focuses on exciting new advances in endocrinology resulting from DNA microarray studies and includes a comprehensive introduction to the use of DNA microarrays in endocrinology. The volume provides the basis for further understanding of the usefulness of microarray analyses in endocrinology research. Topics discussed are the methodology of DNA microarrays and general methods for the analysis of microarray data, as well as studies of a wide variety of normal and abnormal endocrine cells. In the introductory chapter, the volume’s editors describe several issues in hypothesis formulation, experimental design, data analysis, and follow-up studies that may corroborate, validate, and extend hypotheses gained through microarray analyses. The contributed chapters span a variety of applications that we have divided into the areas of (1) genomic insights into molecular mechanisms responsible for hormone action, (2) genomic characterizations of endocrine producing tissues, and (3) genomic manifestations of diseases of hormonal systems. A volume on the cutting-edge of technology, Genomics in Endocrinology will provide researchers with an authoritative volume on the most recent advances in monitoring genome function.