£17.93

VIMENTIN CONCEPTS MOLECULAR (Protein Biochemistry, Synthesis, Structure and Cellular Functions)

Biochemistry

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Description

Intermediate filaments (IFs) are among the main cytoskeleton components in most animal cells, being intermediate in diameter between microtubules and actin filaments. Vimentin is one of the large intermediate filaments (IFs) of eukaryotic cell's cytoskeleton, being the major protein in mesenchymal cells and it is frequently used as a developmental marker of cells and tissues. It may be overexpressed in several cancers, such as lung, breast, head and neck cancer, and sarcomas. Furthermore, it plays a main role in rheumatoid arthritis and Crohn's disease. Thus, this book will address main topics concerning promising therapeutic targets for intestinal fibrosis, vimentin's potential role in epithelial mesenchymal transition (EMT), the role of vimentin in rheumatoid arthritis, vimentin mechanisms and endothelial migration, and EMT and lung neoplasms. Also discussed are insights into the proteomics' field. Many reputed experts worldwide contributed to improvement of this book and it will give readers the state of art regarding vimentin and novel approaches.

Product Specifications

Format: hardcover
ASIN: 1624173594
Category: Books > Subjects > Science, Nature & Maths > Biological Sciences > Biochemistry
Domain: Amazon UK
Release Date: 01 July 2013
Listed Since: 22 November 2012

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VIMENTIN CONCEPTS MOLECULAR (Protein Biochemistry, Synthesis, Structure and Cellular Functions)

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