Humana Host-Pathogen Interactions: Methods and Protocols: 470 (Methods in Molecular Biology, 470)

This book serves as an easy entry point for those investigating the factors responsible for the pathogenicity of microorganisms. The step-by-step laboratory protocols study host-pathogen interaction, with a focus on fungal, bacterial and parasitic pathogens. Review From the reviews: "This book provides an overview of laboratory methods used to evaluate the influence of microbial pathogens on host cells. … This book is written specifically for scientists interested in using new technologies to study host cell reactions to infectious agents. … This is a good, solid techniques book that would be useful to scientific laboratories studying a variety of infectious agents." (Rebecca T. Horvat, Doody’s Review Service, February, 2009) "This book is an excellent collection of protocols for use in the study of host-microbe interaction. The protocols are detailed and accurate. Obviously this is not a book to sit down and read, but one to be used as a source of information for conducting experimental work. … The book will be of use to PhD students and postdoctoral scientists working on host-pathogen interactions. Probably each laboratory working in this area would have a copy rather than each individual." (Tim Mitchell, Microbiology Today, July, 2009) From the Back Cover In recent decades, infectious diseases, once believed to be fairly contained, have become a vital, resurgent field of research.  In Host-Pathogen Interactions: Methods and Protocols, top experts examine the relationship between the host and the pathogen, crucial in the outcome of an infection and the establishment of disease or asymptomatic, commensal colonization by organisms.  The step-by-step laboratory methods and protocols of this volume study host-pathogen interaction, with a focus on fungal, bacterial and parasitic pathogens, at a molecular level in order to reveal the mechanisms of infection and to identify the vulnerabilities of the pathogen of interest.  Written in the highly successful Methods in Molecular Biology™ series format, the chapters feature brief subject introductions, lists of the necessary materials and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Host-Pathogen Interactions: Methods and Protocols serves as an easy entry point for all those investigating the factors responsible for the pathogenicity of microorganisms.