Neuropeptide Receptors (Colloquium Series on Neuropeptides) - Image 1

£76.42

Morgan & Claypool Neuropeptide Receptors (Colloquium Series on Neuropeptides)

Name: Neuropeptide Receptors (Colloquium Series on Neuropeptides)
Brand: Morgan & Claypool
Price: 74.53 GBP
Availability: InStock

Neurology & Clinical Neurophysiology

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Description

Neuropeptides mediate their effects by binding and activating receptors that are responsible for converting these extracellular stimuli into intracellular responses. Most neuropeptides interact with G protein-coupled receptors that transduce the signal by activating heterotrimeric G proteins leading to alterations in second messenger systems to amplify the signal and elicit the intracellular response. In this review, we describe the general structure of G protein-coupled receptors including the information obtained from crystal structure determination that has given an insight into the activation mechanism of these receptors. In addition, we summarize the components of the signal transduction system (including G proteins, effectors and second messengers generally activated by the neuropeptide receptors). Using select examples of neuropeptide-receptor systems, we highlight the neuropeptides and corresponding receptors involved in modulation of pain and analgesia, body weight regulation, and hormonal regulation. Finally, we discuss the enzyme-linked tyrosine kinase receptors activated by growth factors and discuss the emerging concepts in targeting neuropeptide receptors for the identification of novel therapeutics targeting these systems.

Key Features

Pages Count - 168. Binding type - Perfect.

Product Specifications

Brand: Morgan & Claypool
Format: paperback
ASIN: 161504468X
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Neurology & Clinical Neurophysiology
Domain: Amazon UK
Release Date: 01 April 2013
Listed Since: 20 June 2013

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Morgan & Claypool Neuropeptide Receptors (Colloquium Series on Neuropeptides)

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