£76.42

Morgan & Claypool Neuropeptide Receptors (Colloquium Series on Neuropeptides)

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Last 633 days • 633 data points (No recent data available)

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£84.35 £63.07 £67.71 £72.35 £77.00 £81.64 £86.29 09 June 2024 14 November 2024 21 April 2025 26 September 2025 03 March 2026

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39 days 146 days · current 211 days 237 days 0 59 119 178 237 £65-69 £73-77 £77-80 £80-84 Days at Price

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Most common range: £80-84 (237 days, 37.4%)

Price range: £65 - £84

Price levels: 4 price ranges over 633 days

Description

Neuropeptides mediate their effects by binding and activating receptors that are responsible for converting these extracellular stimuli into intracellular responses. Most neuropeptides interact with G protein-coupled receptors that transduce the signal by activating heterotrimeric G proteins leading to alterations in second messenger systems to amplify the signal and elicit the intracellular response. In this review, we describe the general structure of G protein-coupled receptors including the information obtained from crystal structure determination that has given an insight into the activation mechanism of these receptors. In addition, we summarize the components of the signal transduction system (including G proteins, effectors and second messengers generally activated by the neuropeptide receptors). Using select examples of neuropeptide-receptor systems, we highlight the neuropeptides and corresponding receptors involved in modulation of pain and analgesia, body weight regulation, and hormonal regulation. Finally, we discuss the enzyme-linked tyrosine kinase receptors activated by growth factors and discuss the emerging concepts in targeting neuropeptide receptors for the identification of novel therapeutics targeting these systems.

Key Features

Pages Count - 168. Binding type - Perfect.

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