£52.08

Progress in Neurodegeneration: The Role of Metals (Neurodegenerative Diseases-Laboratory and Clinical Research Series)

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£69.32 £30.79 £39.19 £47.60 £56.01 £64.42 £72.82 09 June 2024 11 November 2024 16 April 2025 19 September 2025 22 February 2026

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10 days 54 days 77 days · current 222 days 261 days 0 65 131 196 261 £34-41 £41-48 £48-55 £55-62 £62-69 Days at Price

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Most common range: £62-69 (261 days, 41.8%)

Price range: £34 - £69

Price levels: 5 price ranges over 624 days

Description

This book highlights the role of some metals which induce oxidative stress and imbalances in the neurodegenerative diseases such as Alzheimer disease, Parkinson disease, Amyotrophic Lateral Sclerosis, Huntington Disease, and other dementias. The chemistry and biochemistry of metals induced-oxidative stress, protein damage is first described, followed by the evidence for a pathological role of oxidative stress in these disease states. It is tempting to speculate that free radical oxygen chemistry contributes to pathogenesis in all these conditions, though it is as yet undetermined what types of oxidative changes occur early in the disease, and what types are secondary manifestations of neuronal degeneration. Finally the authors review different metals to describe their specific role in the different pathologies.

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