CRC Press Barile’s Clinical Toxicology: Principles and Mechanisms

As with the two previous editions, Barile’s Clinical Toxicology: Principles and Mechanisms, Third edition, examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. With special emphasis placed on signs and symptoms of diseases and pathology caused by toxins and clinical drugs, the new edition, examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or chemical exposure. The new edition presents the latest, up-to-date protocols for managing various toxic ingestions, and the antidotes and treatments associated with their pathology. In addition, the effect of toxins on a limited number of body systems and drug-induced adverse drug reactions are also covered. KEY FEATURES • Discusses source of the drug or chemical, pharmacological and toxicological mechanisms of action, detection, identification, and treatment • Examines the complex interactions associated with clinical toxicological events • Emphasizes the signs and symptoms of diseases and pathology caused by toxins and clinical drugs • Covers effect of toxins on body systems and drug-induced adverse reactions • Offers a unique perspective for toxicology, pharmacology, pharmacy and health professions students The target audience for this book is undergraduate and graduate toxicology students, clinical pharmacy (Pharm.D.) students, emergency medical personnel, regulatory agencies, and other related health science professionals. It satisfies an essential need for a concise yet detailed authoritative, fundamental text addressing the current principles of clinical toxicology. Review "The stated audience is undergraduate and graduate students, which is appropriate. The book will be a good starting point for understanding basic information on a large number of chemical toxicities." -Udayan Apte, PhD, DABT (University of Kansas Medical Center) DOODY'S PUBLISHERS' CLUB About the Author Frank A. Barile, PhD, is Professor in the Toxicology Division and past chairman of the Department of Pharmaceutical Sciences, St. John’s University College of Pharmacy and Health Sciences, New York. Dr. Barile received his BS in Pharmacy, MS in Pharmacology, and PhD in Toxicology at St. John’s University. After doing a postdoctoral fellowship in Pulmonary Pediatrics at the Albert Einstein College of Medicine, Bronx, NY, he moved to the Department of Pathology, Columbia University―St. Luke’s Roosevelt Hospital, NY, as a research associate. In these positions, he investigated the role of pulmonary toxicants in collagen metabolism in cultured lung cells. In 1984, he was appointed assistant professor in the Department of Health Sciences at City University of NY. Sixteen years later, he rejoined St. John’s University in the Department of Pharmaceutical Sciences in the College of Pharmacy. Dr. Barile holds memberships in several professional associations, including the U.S. Society of Toxicology, the American Association of University Professors, the American Association for the Advancement of Science, the American Society of Hospital Pharmacists, New York City Pharmacists Society, New York Academy of Sciences, and New York State Council of Health System Pharmacists. He is past president of the In Vitro and Alternative Methods Specialty Section of the U.S. Society of Toxicology and a former member of the Scientific Advisory Committee for Alternative Toxicological Methods, the National Institute of Environmental Health Sciences, U.S. National Institutes of Health (NIH). He is former editor of Toxicology in Vitro and Journal of Pharmacological & Toxicological Methods, published by Elsevier Ltd. Dr. Barile is the recipient of Public Health Service research grants from the National Institute of General Medical Sciences, the National Institutes of Health, and grants from private foundations dedicated to alternatives to animal testi