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Humana Developmental and Reproductive Toxicology (Methods in Pharmacology and Toxicology)

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Description

1. Metabolism and Drug-Drug Interaction in Pregnant Mother/Placenta/Fetus Ali S. Faqi and Karsten A. Holm 2. Critical Periods of Development in Teratology Padmanahban Rengasamy 3. Nonclinical Safety Assessment of Developmental and Reproductive Toxicology: Considerations for Conducting Fertility, Embryo-Fetal Development, and Pre- and Postnatal Developmental Toxicology Studies Kevin H. Denny and Ali S. Faqi 4. A Developmental and Reproductive Toxicology Program for Chemical Registration Kamin J. Johnson, Bethany R. Hannas, Sue Marty, Carol L. Zablotny, Jessica LaRocca, Nicholas Ball, and Amanda K. Andrus 5. The Influence of Environmental Contaminants and Lifestyle on Testicular Damage and Male Fertility Sellappan Selvaraju, Meritxell Jodar, and Stephen A. Krawetz 6. Effects of Chemicals on Mammary Gland Development Adam Filgo and Ali S. Faqi 7. Alternative Methods Used to Assess Potential Embryo-Fetal Developmental Risk of Pharmaceuticals Maia L. Green, Joshua Gamse, and Kimberly C. Brannen 8. Using the Alternative Model C. elegans in Reproductive and Developmental Toxicology Studies Daniel Ferreira, Yichang Chen, and Patrick Allard 9. High-Throughput Screens for Embryonic Stem Cells: Stress-Forced Potency-Stemness Loss Enables Toxicological Assays Quanwen Li, Yu Yang, Erica Louden, Elizabeth E. Puscheck, and Daniel A. Rappolee From the Back Cover This meticulous volume covers metabolism and drug-drug interactions during pregnancy, critical periods of developmental toxicology, in vivo and alternative methods to assess potential developmental toxicity for drugs and chemicals, and effects of chemicals on testes and mammary glands. Evaluation of developmental and reproductive toxicology endpoints is an integral part of the safety assessment process for compounds with potential use in women of childbearing age or females that might be exposed during pregnancy  as well as men of reproductive potential. The in vivo assessments included here are guideline-driven and are required for submissions for product approval. Written for the  Methods in Pharmacology and Toxicology series, this collection includes the kind of detailed implementation advice necessary for success in the lab.  Authoritative and practical,  Developmental and Reproductive Toxicology is an ideal resourc e for researchers working in this vital field of study.

Product Specifications

Brand
Humana
Format
hardcover
Domain
Amazon UK
Release Date
18 August 2017
Listed Since
25 April 2017

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