Humana From Melanocytes to Melanoma: The Progression to Malignancy

Part I. Melanocyte Development and Function The Origin and Development of Neural Crest-Derived Melanocytes Debra L. Silver and William J. Pavan MITF: A Matter of Life and Death for Developing Melanocytes Heinz Arnheiter, Ling Hou, Minh-Thanh T. Nguyen, Keren Bismuth, Tamas Csermely, Hideki Murakami, Susan Skuntz, WenFang Liu, and Kapil Bharti MITF: Critical Regulator of the Melanocyte Lineage Erez Feige, Laura L. Poling, and David E. Fisher Melanocytes and the Transcription Factor Sox10 Michael Wegner Human Cutaneous Pigmentation: A Collaborative Act in the Skin, Directed by Paracrine, Autocrine, and Endocrine Factors and the Environment Zalfa A. Abdel-Malek and Ana Luisa Kadekaro Melanocyte Distribution and Function in Human Skin: Effects of Ultraviolet Radiation Yuji Yamaguchi and Vincent J. Hearing Part II. Melanocyte Transformation and Progression to Melanoma Altered Signal Transduction in Melanoma Pablo López Bergami, Anindita Bhoumik, and Ze'ev Ronai BRN2 in Melanocytic Cell Development, Differentiation, and Transformation Anthony L. Cook, Glen M. Boyle, J. Helen Leonard, Peter G. Parsons, and Richard A. Sturm The Dynamic Roles of Cell-Surface Receptors in Melanoma Development Dong Fang and Meenhard Herlyn Familial Melanoma Genes, Melanocyte Immortalization, and Melanoma Initiation Dorothy C. Bennett Genetic Progression From Melanocyte to Malignant Melanoma Boris C. Bastian The Multiple Roles of the Oncogenic Protein SKI in Human Malignant Melanoma Dahu Chen, Qiushi Lin, I. Saira Mian, Jon Reed, and Estela E. Medrano RB/E2F Regulation and Dual Activity in the Melanocytic System Ruth Halaban Melanoma Development and Pigment Cell Transformation Claudia Wellbrock The Biology and Genetics of Melanoma Norman E.Sharpless and Lynda Chin The Biology of Xeroderma Pigmentosum: Insights Into the Role of Ultraviolet Light in the Development of Melanoma James E. Cleaver Divergent Pathways to Cutaneous Melanoma David C. Whiteman and Adèle C. Green Pigmentation, DNA Repair, and Candidate Genes: The Risk of Cutaneous Malignant Melanoma in a Mediterranean Population Maria Teresa Landi Low-Penetrance Genotypes, Pigmentation Phenotypes, and Melanoma Etiology Peter A. Kanetsky and Timothy R. Rebbeck The Biology of Melanoma Progression: From Melanocyte to Metastatic Seed A. Neil Crowson, Cynthia Magro, and Martin C. Mihm, Jr. Optical Imaging Analysis of Atypical Nevi and Melanoma Amanda Pfaff Smith and Dorothea Becker Proteomics Analysis of Melanoma Cell Lines and Cultured Melanocytes Katheryn A. Resing and Natalie G. Ahn Part III. Primary Invasive Melanoma to Metastatic Melanoma Paradigm of Metastasis for Malignant Melanoma Stanley P. L. Leong Repair of UV-Induced DNA Damage and Melanoma Risk Qingyi Wei High-Risk Factors for Melanoma Metastasis Neil A. Accortt and Seng-jaw Soong Role of Melanoma Inhibitory Activity in Early Development of Malignant Melanoma Anja-Katrin Bosserhoff Role and Regulation of PAR-1 in Melanoma Progression Carmen Tellez and Menashe Bar-Eli Molecular Mechanisms of Melanoma Metastasis Mohammed Kashani-Sabet Overview of Tumor Progression in Melanoma David E. Elder The Plasticity of Melanoma Cells and Associated Clinical Implications Mary J. C. Hendrix, Elisabeth A. Seftor, Angela R. Hess, and Richard E. B. Seftor The Clinical Use of Molecular Markers as Predictors of Disease Outcome and Response to Therapy in Malignant Melanoma Steve R. Martinez, Hiroya Takeuchi, Dave S. B. Hoon The Role Review From the reviews: "...this compendium of current thinking is recommended reading for anyone with an interest in pigmentation and cancer and a valuable resource for any library." -Melanoma Research "This book, the first of its kind on melanoma, details the current state of our knowledge … . should be viewed as an important resource for understanding the broad field of melanocyte and melanoma biology. Newcomers to the field … will find this book extremely useful. … This book captures the trem