Springer Precision Molecular Pathology of Breast Cancer: 10 (Molecular Pathology Library, 10)

This volume provides a comprehensive review of the molecular mechanisms involved in precancerous lesions and benign and malignant breast tumors. Given the complex molecular pathways in breast cancer biology, the book simplifies these complex mechanisms and highlights the practical issues important for daily practice. Sections are structured to review breast carcinogenesis and the role of familial predisposition and stem cells in initiation and progression of breast cancer. In-depth chapters present morphologic and molecular correlations in precancerous and malignant breast lesions, while outlining highly practical issues that are in practice today in breast pathology, such as evaluation of estrogen, progesterone receptors, and HER-2. Written by experts in the field, Precision Molecular Pathology of Breast Cancer is a valuable resource that covers the current practice of breast pathology and looks into the future with an emphasis on the molecular basis of breast cancer. Review “For pathologists and other physicians looking for a good, comprehensive reference on the molecular pathology of breast lesions, this book offers a good summary of this complex field. Chapters are overall well written, making this a reader friendly resource for pathologists who deal with the interpretation of these molecular findings. This book would be a valuable addition to a departmental and personal library.” (Ana G. Yuil-Valdes, Doody’s Book Reviews, November, 2015) From the Back Cover This volume provides a comprehensive review of the molecular mechanisms involved in precancerous lesions and benign and malignant breast tumors. Given the complex molecular pathways in breast cancer biology, the book simplifies these complex mechanisms and highlights the practical issues important for daily practice. Sections are structured to review breast carcinogenesis and the role of familial predisposition and stem cells in initiation and progression of breast cancer. In-depth chapters present morphologic and molecular correlations in precancerous and malignant breast lesions, while outlining highly practical issues that are in practice today in breast pathology, such as evaluation of estrogen, progesterone receptors, and HER-2.   Written by experts in the field, Precision Molecular Pathology of Breast Cancer is a valuable resource that covers the current practice of breast pathology and looks into the future with an emphasis on the molecular basis of breast cancer. About the Author Ashraf Khan, MD, FRCPathUniversity of Massachusetts Medical School, Department of Pathology, Worcester, MA, USA Ian O. Ellis, MD, FRCPathUniversity of Nottingham, Department of Histopathology, Nottingham City Hospital, Nottingham, UK Andrew M. Hanby, BM, FRCPathSt. James University Hospital/University of Leeds, Leeds Institute of Cancer and Pathology, Leeds, West Yorkshire, UK Ediz F. Cosar, MDUMassMemorial Medical Center, University of Massachusetts Medical School, Department of Pathology, Worcester, MA, USA Emad Rakha, MD, PhD, FRCPathUniversity of Nottingham, Department of Histopathology, Nottingham City Hospital, Nottingham, UK Dina Kandil, MDUMassMemorial Medical Center, University of Massachusetts Medical School, Department of Pathology, Worcester, MA, USA