Immunogenetics of Autoimmune Disease (Medical Intelligence Unit) - Image 1

£107.98

Springer Immunogenetics of Autoimmune Disease (Medical Intelligence Unit)

Name: Immunogenetics of Autoimmune Disease (Medical Intelligence Unit)
Brand: Springer
Price: 107.27 GBP
Availability: InStock

Immunology

Price History & Forecast

Last 88 days • 88 data points

Historical

Generating forecast...

Price Distribution

Price distribution over 88 days • 3 price levels

Days at Price

Current Price

Price Analysis

Most common price: £107 (76 days, 86.4%)

Price range: £106 - £108

Price levels: 3 different prices over 88 days

Description

utoimmunity is the downstream outcome of a rather extensive and coordinated series of events that include loss of self-tolerance, peripheral lymphocyte Aactivation, disruption of the blood-systems barriers, cellular infiltration into the target organs and local inflammation. Cytokines, adhesion molecules, growth factors, antibodies, and other molecules induce and regulate critical cell functions that perpetuate inflammation, leading to tissue injury and clinical phenotype. The nature and intensity of this response as well as the physiological ability to restore homeostasis are to a large extent conditioned by the unique amino acid sequences that define allelic variants on each of the numerous participating mol ecules. Therefore, the coding genes in their germline configuration play a primary role in determining who is at risk for developing such disorders, how the disease progresses, and how someone responds to therapy. Although genetic components in these diseases are clearly present, the lack of obvious and homogeneous modes of transmission has slowed progress by prevent ing the full exploitation of classical genetic epidemiologic techniques. Furthermore, autoimmune diseases are characterized by modest disease risk heritability and m- tifaceted interactions with environmental influences. Yet, several recent discoveries have dramatically changed our ability to examine genetic variation as it relates to human disease. In addition to the development of large-scale laboratory methods and tools to efficiently recognize and catalog DNA diversity, over the past few years there has been real progress in the application of new analytical and data-manage ment approaches.

Product Specifications

Brand: Springer
Format: paperback
ASIN: 1489997482
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Immunology
Domain: Amazon UK
Release Date: 13 December 2014
Listed Since: 17 December 2014

Barcode

No barcode data available

Springer Immunogenetics of Autoimmune Disease (Medical Intelligence Unit)

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

The Immunogenetics of Autoimmune Diseases, Volume II: 002

Genetics of Autoimmunity: 267 (Novartis Foundation Symposia)

Autoimmunity

The Autoimmune Diseases

Autoimmunity

New Research on Autoantibodies - Nova Science Publishers Inc

Auto-Immunity and Auto-Immune Disease: A survey for physician or biologist

Encyclopedia of Medical Immunology: Immunodeficiency Diseases

The Rose and Mackay Textbook of Autoimmune Diseases

Encyclopedia of Medical Immunology: Allergic Diseases

The Autoimmune Diseases

Genetics of Rare Autoimmune Diseases (Rare Diseases of the Immune System)

The Impact of Biotechnology on Autoimmunity: 6 (Medical Science Symposia Series, 6)

Springer Gene Therapy of Autoimmune Disease Medical Intelligence

Humana Autoimmunity: Methods and Protocols - 900 Series

The Epigenetics of Autoimmunity (Volume 5) (Translational Epigenetics, Volume 5)

Autoimmunity, COVID-19, Post-COVID19 Syndrome and COVID-19 Vaccination (Volume 1) (Future of Autoimmunity Research, Volume 1)

New Concepts in Pathology and Treatment of Autoimmune Disorders: 7 (Ernst Schering Foundation Symposium Proceedings, 7)

Mechanisms of Lymphocyte Activation and Immune Regulation VIII: Autoimmunity 2000 and Beyond: 490 (Advances in Experimental Medicine and Biology)

Autoantibodies

The Autoimmune Diseases

Autoimmune Disease Diagnosis: Systemic and Organ-specific Diseases

Autoimmunity, Part D: Autoimmune Disease, Annus Mirabilis, Volume 1108 (Annals of the New York Academy of Sciences)

Mechanisms of Lymphocyte Activation and Immune Regulation VIII: Autoimmunity 2000 and Beyond: 490 (Advances in Experimental Medicine and Biology, 490)