Prions and Diseases: Volume 2, Animals, Humans and the Environment - Image 1

£199.42

Springer Prions and Diseases: Volume 2, Animals, Humans and the Environment

Name: Prions and Diseases: Volume 2, Animals, Humans and the Environment
Brand: Springer
Price: 199.42 GBP
Availability: InStock

Neurology & Clinical Neurophysiology

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Description

Volume II covers the etiology, pathogenesis, classification, histopathological and clinical aspects of animal and human prion diseases, including decontamination of prions and development of therapeutics for prion diseases, such as immunomodulation. From the Back Cover Transmissible spongiform encephalopathies (TSE), now broadly known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. However, the nature of the transmissible agent had largely remained a mystery until Stanley Prusiner discovered the infectious isoform of the prion protein (PrP), named prion or scrapie PrP (PrPSc), in 1982. The subsequent modern studies with protein chemistry and molecular biology in cell culture, transgenic animals, and cell-free systems, including the revolutionary protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In Prions and Prion Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date development in many aspects of these unique infectious pathogens and their associated diseases. Volume II features a variety of animal and human prion diseases, including the newly-identified atypical forms of bovine spongiform encephalopathy and scrapie in animals, and variably protease-sensitive prionopathy in humans, prions in the environment, Tau pathology in human prion disease, transmission of the disease by blood transfusion, mammalian and non-mammalian models, conventional and advanced diagnoses, prion-specific antibodies, as well as decontamination of prions and development of therapeutics of prion diseases, such as the application of immunomodulation. This volume provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the highly publicized animal and human prion diseases.

Product Specifications

Brand: Springer
Format: paperback
ASIN: 1489993975
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Neurology & Clinical Neurophysiology
Domain: Amazon UK
Release Date: 13 December 2014
Listed Since: 04 December 2014

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Springer Prions and Diseases: Volume 2, Animals, Humans and the Environment

About as cheap as it gets. The only time it was cheaper was 1 year ago.

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