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£107.98

Springer Cell-Extracellular Matrix Interactions in Cancer

Name: Cell-Extracellular Matrix Interactions in Cancer
Brand: Springer
Price: 107.98 GBP
Availability: InStock

Oncology

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Description

This book describes how extracellular matrix components (ECM) create a niche for tumor formation. It also discusses the contribution of ECM components and their respective receptors in the development and spread of cancer. From the Back Cover Cells require interactions with extracellular matrix (ECM) components in order to undergo normal morphogenesis with respect to organogenesis. ECM plays a significant role in regulating numerous cellular functions, like cell shape, adhesion, migration, proliferation, polarity, differentiation and apoptosis. In pathological conditions such as cancer, increased synthesis of certain ECM components and/or increased breakdown with consequent generation of ECM cleavage products can contribute to cancer growth and progression. That many growth factors (i.e. FGF, VEGF) are stored in the ECM milieu and are released upon protease-dependent cleavage further confirms the importance of ECM in regulating cell functions. Cell-Extracellular Matrix Interactions in Cancer describes how ECM creates a niche for tumor formation and the contribution of ECM components and their respective receptors in the development and spread of cancer.

Product Specifications

Brand: Springer
Format: paperback
ASIN: 1489981128
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Oncology
Domain: Amazon UK
Release Date: 28 November 2014
Listed Since: 29 November 2014

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Springer Cell-Extracellular Matrix Interactions in Cancer

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