Humana Mass Spectrometry in Biology & Medicine

Leading practitioners detail revolutionary new spectrometric techniques for the identification and covalent structural characterization of macromolecules, proteins, glycoconjugates, and nucleic acids. Based on the Fourth International Symposium on Mass Spectrometry in the Health and Life Sciences held in San Francisco in 1998, this invaluable book contains tested strategies for solving many significant biomedical research problems. The techniques use mass spectrometry, automated computer processing of spectral information, and gene, protein, and EST databases for genomic and proteomic correlations. Mass Spectrometry in Biology and Medicine offers a unique opportunity to explore and apply these new techniques of mass spectrometry that are revolutionizing the identification and structural characterization of proteins, carbohydrates, and nucleic acids. Review ". . .of significant reference value. . . " -Journal of the American Society of Mass Spectrometry ". . .a valuable addition to the library of anyone working in the area of biomolecule characterization by mass spectrometry." -The Analyst ". . .the writing and explanation are first rate. . ." -Trends in Analytical Chemistry "The purpose is to provide an overview of mass spectrometry. This worthy objective has been met. . . In 27 chapters the editors provide a very useful overview of the application of mass spectrometric methods to a wide variety of biological problems."-Doody's Health Sciences Book Review Journal In 27 chapters the editors provide a very useful overview of the application of mass spectrometric methods to a wide vaiety of biological problems. Examples include determination of purity, molecular weight, presence of posttranslational modifications (glycosylation, phosphorylation), ligand binding, sequencing of peptides, coupling of purification protocols (capillary electrophoresis, for example) and the use of tandem spectrometers.-Doody's Health Sciences Book Review Journal From the Back Cover In Mass Spectrometry in Biology and Medicine, leading practitioners detail revolutionary new spectrometric techniques for the identification and covalent structural characterization of macromolecules, proteins, glycoconjugates, and nucleic acids. Based on the Fourth International Symposium on Mass Spectrometry in the Health and Life Sciences held in San Francisco in1998, this invaluable book contains tested strategies for solving many significant biomedical research problems. The techniques use mass spectrometry, automated computer processing of spectral information, and gene, protein, and EST databases for genomic and proteomic correlations. Mass Spectrometry in Biology and Medicine offers a unique opportunity to explore and apply the new techniques of mass spectrometry that are revolutionizing the identification and structural characterization of proteins, carbohydrates, and nucleic acids. Its authoritative assessment of the field-and how to solve important and challenging problems throughout bioscience, medicine, and drug discovery-ensures a competitive advantage for today's knowledgeable researchers.