Maurie Markman and a panel of distinguished clinicians and leading clinical investigators comprehensively review the current status of regional antineoplastic drug delivery in the management of malignant disease. These authorities present a critical analysis of both the rationale and limitations of regional therapy and discuss potential clinical trials designed to explain the effectiveness of this method of therapy in special settings. Their presentations describe many exciting and innovative strategies for using regional drug delivery in anticancer therapy, including coverage of such areas of special interest as colorectal, skin, lung, pancreatic, ovarian, and gastrointestinal cancers. Comprehensive and authoritative, Regional Chemotherapy: Clinical Research and Practice offers surgical and medical oncologists and clinical cancer investigators a gold-standard review of the current role and future development of this increasingly powerful weapon in the battle against cancer. Review "This book features a relatively thorough discussion of regional chemotherapy in most body cavities, and for most diseases for which there is a current use. Extensive coverage of intraperitoneal chemotherapy for ovarian and gastrointestinal cancers, mesothelioma, is a strength of the text. Likewise, isolated limb and organ perfusion are extensively covered. . . This is a good book with a good purpose. . .it is comprehensive and can be a useful guide in caring for the individual patient or implementing a new approach to treatment in general. Some otherwise hard to find information is presented in this book, which may help in the general dissemination of and use of these therapies. "-Doody's Health Sciences Book Review Journal "The promising and highly innovative approaches to the management of malignant diseases that employ regional drug delivery have been reported during past several years. This book provides an excellent state-of-the-art of this topic....many distinguished contributors-the leading clinicians and clinical investigators discuss in depth all clinical aspects of intrahepatic chemotherapy, isolated limb perfusion, intravesical, intraventricular and intrathccal application of antincoplastic drugs as well as the intracavitary chemotherapy." - Neoplasma "Specific malignant disease settings are exhaustively discussed, and while the local/regional therapeutic approach is advocated throughout, other, more traditional, strategies are also discussed, as is regional drug delivery as part of a multidisciplinary management effort in the most complex tumor forms....The book also includes an important topical chapter on intraperitoneal biological therapies for ovarian cancer, and researchers in this area will appreciate the wealth of recent biological references...The methods and the chemotherapies described, illustrated by a number of useful figures, will provide a good source of reference for oncologists, surgeons, gynaecologists, haematologists and other oncological specialists seeking to enrich their understanding and hone their skills in this rapidly expanding sector."...Retinoids "Rather than encouraging open acceptance of sophisticated, challenging techniques, the authors of each chapter cautiously present pros, cons, and the pitfalls of promising areas in cancer therapy. Few if any individual text books in the field of surgical oncology have focused solely on this developing field of cancer treatment. A surgeon or oncologist interested in an initial review of the subject will be rewarded with a clinical treatise that advances new cancer treating strategies." - Arch Surg From the Back Cover In Regional Chemotherapy: Clinical Research and Practice, Maurie Markman and a panel of distinguished clinicians and leading clinical investigators comprehensively review the current status of regional antineoplastic drug delivery in the management of malignant disease. These authorities present a cri
