CRC Press Heterogeneous Catalysis: A Versatile Tool for the Synthesis of Bioactive Heterocycles

Product Description For more than a century, bioactive heterocycles have formed one of the largest areas of research in organic chemistry. They are important from a biological and industrial point of view as well as to the understanding of life processes and efforts to improve the quality of life. Heterogeneous Catalysis: A Versatile Tool for the Synthesis of Bioactive Heterocycles highlights the recent methodologies used in the synthesis of such bioactive systems and focuses on the role of heterogeneous catalysis in the design and synthesis of various biologically active heterocyclic compounds of pharmacological interest. Topics include: Synthetic protocols for the construction of heterocyclic systems employing silica-bound catalysts Recent advances in heterogeneous copper-catalyzed reactions for the synthesis of bioactive heterocycles Features of silica-based heterogeneous catalysts, such as abundance, ease of use, and stability Ultrasound as an effective tool for accelerating reactions Organic transformations catalyzed by nano-ZnO as a valuable heterogeneous catalyst Heterogeneous catalysts employed in the synthesis of coumarins Heterocyclizations in the presence of silver salts Home-made organometallic silica sources, known as silatranes Reflecting the focused studies currently conducted in these areas, the book also examines anticancer, antifungal, antibacterial, anti-HIV, anti-inflammatory, antioxidant, and many more biological activities of heterocyclic compounds. It is essential reading for postgraduate and research scholars in the fields of biochemistry, chemical biology, medicinal chemistry and pharmaceutical chemistry. About the Author K. L. Ameta received his doctorate degree in organic chemistry from M. L. Sukhadia University, Udaipur, India. He is assistant professor of chemistry in the Faculty of Arts, Science and Commerce, Mody Institute of Technology and Science, Deemed University, Lakshmangarh, Rajasthan, India. His research area is the synthesis, characterization, and biological evaluation of bioactive heterocyclic systems of different sizes. In addition, he has keen interest in heterogeneous catalyzed organic synthesis and photocatalysis. He has published a number of research articles in various journals of national and international repute. Andrea Penoni is assistant professor in organic chemistry at the Department of Science and High Technology at the University of Insubria, Italy. He received a PhD from the University of Milan. He did his postdoctoral training at the University of Milan, and at the University of Oklahoma, where he studied annulation reactions between nitro- and nitrosoaromatics with alkynes. Since 2003, he has been a faculty member at the University of Insubria (Como). His research is particularly focused on the synthesis of heterocycles, naturally occurring compounds, and potentially bioactive molecules. He is also involved in research projects on the carbon–nitrogen bond formation mediated by metals and metal complexes and in the synthesis of nitrogen-containing heterocycles by metathesis reactions.