Humana The Beta-Adrenergic Receptors (The Receptors)

John Perkins' timely new volume on The Beta-Adrenergic Receptors brings to light the latest information on this key receptor class-the prototype of a family of receptors that regulate the activity of G-proteins. The first of its type to be cloned and sequenced, this receptor class has been the subject of much fruitful study. The clinical significance of the beta-adrenergic receptors hinges on their usefulness as targets for drugs to control asthma, hypertension, and cardiovascular disease. The Beta-Adrenergic Receptors covers a variety of topics, including: structure-function relationships ? ligand-induced desensitization of b-adrenergic receptors ? reconstitution of b-adrenergic receptors ? biochemical functions ? antibodies to b-adrenergic receptors ? autoradiographic studies ? b-adrenergic receptors in pathophysiological states ? clinical applications ? drug and hormonal regulation of the b-adrenergic receptor. The Beta-Adrenergic Receptors is an indispensable resource for biochemists, molecular biologists, pharmacologists, physiologists, neuroscientists, and others involved with the study of receptors at either the research or clinical level. Review The chapters can be most warmly recommended to all who are active in fundamental and clinical research.-Arzneimittel-Forschung-Drug Research