£146.46

About as cheap as it gets — within 5% of the all-time low it hit 1 month ago.

£146 today · all-time low £144 (Sep 2026) · usually £147

Springer Polyomaviruses and Human Diseases: 577 (Advances in Experimental Medicine and Biology, 577)

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£148.21 £143.50 £144.53 £145.56 £146.58 £147.61 £148.64 28 July 2026 16 August 2026 05 September 2026 25 September 2026 15 October 2026
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15 days 11 days · current 54 days 0 14 27 41 54 £144 £146 £148 Days at Price

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Most common price: £148 (54 days, 67.5%)

Price range: £144 - £148

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Description
Science never solves apr oblem without creating ten more Geor ge Bernard Shaw How prophetic the above words prove to be when applied to the advances of 20th century medicine. Prior to Banting and Best, chnicians were unaware of the ravages of diabetes, patients simply wasted away and died. Following the purifica tion of insulin, clinicians now had to deal with diabetic retinopathy, diabetic neph ropathy and all the other complications of long-term diabetes. A little over 50 years ago, the first successful human kidney transplant was performed in Boston. The first 30 years of the experience had successes when compared to the alternative but were a constant struggle to get even 50% of the grafts from deceased donors to survive more than a year. However, the science continued to advance knowledge of the immune response. With this came more and increasingly powerful tools for the clinician. Suddenly, success rates of 80-90% at one year were attainable. With this success came new problems, new complications and clinicians now had to worry about the long-term consequences of their therapy as patients were surviving with functional grafts for extended periods. A particular infectious complication evolved with the application of ever more powerful immunosuppressant drugs. Astute clinicians noted that occasionally cellular rejections seemed to get worse with steroids. Despite their best efforts and the use of powerful drugs, patients lost their grafts to overwhelming interstitial infiltrates not seen before.

Product Specifications
Brand
Springer
Format
paperback
ASIN
1441921222
Category
Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Immunology
Domain
Amazon UK
Release Date
19 November 2010
Listed Since
06 July 2010

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