£117.40

Springer Synaptic Plasticity in Pain

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Last 583 days • 583 data points (No recent data available)

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£140.00 £109.64 £116.26 £122.89 £129.51 £136.14 £142.76 09 June 2024 01 November 2024 27 March 2025 19 August 2025 12 January 2026

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21 days 143 days · current 5 days 28 days 43 days 98 days 49 days 6 days 190 days 0 48 95 143 190 £112 £117 £120 £129 £132 £133 £135 £137 £140 Days at Price

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Most common price: £140 (190 days, 32.6%)

Price range: £112 - £140

Price levels: 9 different prices over 583 days

Description

Primary sensory neurons respond to peripheral stimulation and project to the spinal cord. Specifically, the population of neurons which respond to damaging stimuli terminate in the superficial layers of the dorsal horn. Therefore, the dorsal horns constitute the first relay site for nociceptive fibre terminals which make synaptic contacts with second order neurons. It has recently become clear that the strength of this first pain synapse is plastic and modifiable by several modulators, including neuronal and non-neuronal regulators, and studies on the fundamental processes regulating the plasticity of the first pain synapse have resulted in the identification of new targets for the treatment of chronic pain. This book will be of interest to a wide readership in the pain field.

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