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CRC Press Revival: Transformation of Human Epithelial Cells (1992): Molecular and Oncogenetic Mechanisms (CRC Press Revivals)

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Description

This book offers a conceptual explanation of the interrelationships that exist between the stages in the progression of initiated epithelial cells in culture compared with the diverse tissue of organs and the progression of tumors from different organ sites. The fate of the modification of adducts is discussed at the molecular level. The role that modifications in hot spots in oncogenes and supressor genes play at the molecular level and how these molecular modifications can lead to an explanation of molecular control in the formation of tumor phenotypes is also examined. Researchers in cell biology and toxicology, applied pharmacology, carcinogenesis, teratogenesis, mutagenesis, and molecular toxicology will find the book useful, interesting reading. About the Author George E. Milo was named Professor Emeritus at The Ohio State University, and in 2010 was recognized as an Outstanding Alumni of the University of Vermont.

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