CRC Press Micro Reaction Technology in Organic Synthesis

While continuous processes have found widespread application within chemical production, members of the research and development communities have historically favored the centuries old technique of iterative batch reactions. With the exception of combinatorial and microwave chemistry, little had been done to change the way that synthetic chemists conduct their research. However, today’s synthetic chemist is under increasing pressure to discover and deliver compounds quickly, with an eye on devising scalable synthetic methodologies. An up-to-date account of recent developments in continuous flow organic synthesis, Micro Reaction Technology in Organic Synthesis is a useful resource for those both new to, and actively researching within, the field of micro reaction technology. Written by chemists for chemists, key synthetic information takes precedence over technological details Highlights the advantages and disadvantages of the technology, giving the reader an idea of where future research needs to be targeted Presents a comprehensive collection of synthetic reactions that have been investigated over the past decade, therefore is a one-stop resource to the reactions and techniques that have been investigated so far With an ever increasing number of commercial flow reaction platforms available, this book highlights the current state of the technology with the vision that more synthetic chemists will embark upon flow chemistry programs of research, facilitating the identification of novel synthetic methodologies the potential to be scaled directly to production. Review "Although there have been several books devoted to Micro Reaction Technology over the past decade, there has not been a volume focussed on the needs of the organic chemist. This excellent new book fulfils that gap."―Trevor Laird, in Organic Process Research, March 2011 "In contrast to some of the other books available on this subject, this is clearly a book written by chemists for chemists. In a relatively short and easy-to-follow introductory chapter, the fundamentals of micro reaction technology, including fabrication of devices, pumping and mixing issues, and advantages/disadvantages, are explained with the synthetic chemist in mind. In each of tile sub chapters, the reader is pointed toward appropriate key references, review articles, or other books that provide further details on the subject."―American Chemical Society, 2011 About the Author Charlotte Wiles, Paul Watts